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945216-88-6

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945216-88-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 945216-88-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,5,2,1 and 6 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 945216-88:
(8*9)+(7*4)+(6*5)+(5*2)+(4*1)+(3*6)+(2*8)+(1*8)=186
186 % 10 = 6
So 945216-88-6 is a valid CAS Registry Number.

945216-88-6Downstream Products

945216-88-6Relevant articles and documents

3,4-Dihydro-2H-benzo[1,4]oxazine derivatives as 5-HT6 receptor antagonists

Zhao, Shu-Hai,Berger, Jacob,Clark, Robin D.,Sethofer, Steven G.,Krauss, Nancy E.,Brothers, Julie M.,Martin, Renee S.,Misner, Dinah L.,Schwab, Dietmar,Alexandrova, Ludmila

, p. 3504 - 3507 (2008/02/09)

A series of novel 3,4-dihydro-2H-benzo[1,4]oxazine derivatives has been designed and synthesized as 5-HT6 receptor antagonists. Many of the compounds displayed subnanomolar affinities for the 5-HT6 receptor and good brain penetration in rats. The relationship of structure and lipophilicity to hERG inhibition of this series of compounds is discussed.

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