945247-22-3

Upstream product

• 16495-03-7 (S)-4-(benzyloxymethyl)-2,2-dimethyl-1,3-dioxolane 
• 100-39-0 benzyl bromide 
• 56552-80-8 (R)-3-benzyloxy-1,2-propanediol 
• 142924-97-8 1-O-(9z)-octadenoyl-3-benzylglycerol 
• 57-10-3 1-hexadecylcarboxylic acid 

Downstream Products

• 64199-61-7 1-O-oleoyl-2-O-palmitoyl-sn-glycerol 

Relevant academic research and scientific papers

ONE-POT SYNTHESIS OF ALPHA/BETA-O-GLYCOLIPIDS

The present invention provides a one-pot method of preparing an unprotected α-O-glycolipid. The first step involves contacting a protected α-iodo sugar with a catalyst and a lipid comprising a hydroxy group, under conditions sufficient to prepare a protected α- O-glycolipid. The second step involves deprotecting the protected α-O-glycolipid under conditions sufficient to prepare the unprotected α-O-glycolipid, wherein the contacting and deprotecting steps are performed in a single vessel. The present invention also provides a one-pot method of preparing an unprotected β-O-glycolipid following the steps for the preparation of the unprotected α-O-glycolipid.

Efficient, one-pot syntheses of biologically active α-linked glycolipids

Per-O-silylated galactosyl iodides undergo α-glycosidation with fully functionalized glycolipids producing biologically relevant conjugates. The Royal Society of Chemistry.