945261-73-4Relevant academic research and scientific papers
Triazolopiperazine-amides as dipeptidyl peptidase IV inhibitors: Close analogs of JANUVIA (sitagliptin phosphate)
Kim, Dooseop,Kowalchick, Jennifer E.,Edmondson, Scott D.,Mastracchio, Anthony,Xu, Jinyou,Eiermann, George J.,Leiting, Barbara,Wu, Joseph K.,Pryor, KellyAnn D.,Patel, Reshma A.,He, Huaibing,Lyons, Kathryn A.,Thornberry, Nancy A.,Weber, Ann E.
, p. 3373 - 3377 (2008/02/07)
A series of β-aminoamides bearing triazolopiperazines has been prepared and evaluated as potent, selective, orally active dipeptidyl peptidase IV (DPP-4) inhibitors. Efforts at optimization of the β-aminoamide series, which ultimately led to the discovery
