141060-00-6

Basic information

• Product Name: 2,4-Difluorophenyl acetic acid
• Synonyms: 2,4-Difluorophenylacetylchloride99%
• CAS NO: 141060-00-6
• Molecular Formula: C₈H₅ClF₂O
• Molecular Weight: 190.5745064
• Mol File: 141060-00-6.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,4-Difluorophenyl acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Difluorophenyl acetic acid(141060-00-6)
• EPA Substance Registry System: 2,4-Difluorophenyl acetic acid(141060-00-6)

Safety Data

• Hazardous Substances Data: 141060-00-6(Hazardous Substances Data)

Usage

Description

2,4-Difluorophenyl acetic acid, also known as Diflunisal, is a nonsteroidal anti-inflammatory drug (NSAID) characterized by its ability to relieve pain and reduce inflammation. It functions by inhibiting the production of prostaglandins, which are the body's chemicals responsible for causing pain and inflammation.

Uses

Used in Pharmaceutical Industry:
2,4-Difluorophenyl acetic acid is used as an analgesic and anti-inflammatory agent for the treatment of various conditions such as arthritis, gout, and muscle pain. Its mechanism of action involves the inhibition of prostaglandin production, thereby reducing pain and inflammation associated with these conditions.
Used in Pain Management:
2,4-Difluorophenyl acetic acid is used as a pain reliever to alleviate discomfort caused by different types of pain, including chronic and acute pain conditions. Its effectiveness in reducing inflammation and pain makes it a valuable component in pain management therapies.
Used in Inflammation Reduction:
2,4-Difluorophenyl acetic acid is utilized as an anti-inflammatory agent to decrease inflammation in the body. By inhibiting the production of prostaglandins, it helps in reducing the swelling and redness associated with inflammatory conditions.

Upstream product

• 79-37-8 oxalyl dichloride 
• 81228-09-3 2,4-difluorophenylacetic acid 

Downstream Products

• 916765-72-5 [2-(2,4-Difluoro-phenyl)-acetyl]-thiourea 
• 708276-18-0 2-(2,4-difluorophenyl)-1-(4-methylsulfanylphenyl)ethanone 
• 194240-96-5 ethyl 4-(2,4-difluorophenyl)-3-oxobutanoate 
• 1616278-56-8 tert-butyl (5-(5-(2,4-difluorobenzyl)-1,3,4-thiadiazol-2-yl)-2-(ethylcarbamoyl)-3-methoxy-4-oxopyridin-1(4H)-yl)(methyl)carbamate 
• 1616277-97-4 tert-butyl 2-(2-(2,4-difluorophenyl)ethanethioyl)hydrazine-1-carboxylate 
• 1616277-81-6 C₂₆H₂₈F₂N₄O₄S 
• 1616278-55-7 C₂₇H₃₀F₂N₄O₄S 
• 1616278-54-6 C₂₇H₃₀F₂N₄O₄S 
• 1616277-62-3 C₂₄H₂₃F₂N₅O₄S 

Relevant articles and documents

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Method for preparing acyl chloride by catalyzing phosgene and acid

The invention discloses a method for preparing acyl chloride by catalyzing phosgene and acid. The method includes the following steps that 1, with carboxylic acid as a raw material, a catalyst and a solvent are added, and under the condition that the temperature is maintained to range from 20 DEG C to 200 DEG C, phosgene is introduced into a reaction flask for a reaction; 2, after the molar ratio of carboxylic acid to phosgene reaches 1:1.0-1:10, phosgene introduction is stopped, reacted mixed liquor is obtained and filtered, obtained filter liquor is subjected to reduced pressure distillation at a high vacuum degree to obtain acyl chloride, and an obtained filter cake continues to serve as the catalyst in the step 1 to be recycled. Compared with an existing catalyst adopted for preparing acyl chloride according to a phosgene method, the catalyst used in the method is small in dosage, convenient to recycle, easy to separate from a product, better in product quality, safe, stable and environmentally friendly, generated solid waste is greatly reduced, the experience of operators is greatly improved, and safety risks are lowered.