945262-32-8 Usage
General Description
3-CYCLOPROPYL-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[4,3-A]PYRAZINE is a chemical compound with the molecular formula C8H12N4. It is a heterocyclic compound containing a cyclopropyl ring and a triazolopyrazine ring system. 3-CYCLOPROPYL-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[4,3-A]PYRAZINE has potential pharmaceutical applications and is being studied for its potential use as a drug candidate. Its unique structure and properties make it an interesting target for medicinal chemistry research, and its potential biological activity is of interest for drug development. Further research is ongoing to explore its potential uses in various areas of medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 945262-32-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,5,2,6 and 2 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 945262-32:
(8*9)+(7*4)+(6*5)+(5*2)+(4*6)+(3*2)+(2*3)+(1*2)=178
178 % 10 = 8
So 945262-32-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H12N4/c1-2-6(1)8-11-10-7-5-9-3-4-12(7)8/h6,9H,1-5H2
945262-32-8Relevant articles and documents
Triazolopiperazine-amides as dipeptidyl peptidase IV inhibitors: Close analogs of JANUVIA (sitagliptin phosphate)
Kim, Dooseop,Kowalchick, Jennifer E.,Edmondson, Scott D.,Mastracchio, Anthony,Xu, Jinyou,Eiermann, George J.,Leiting, Barbara,Wu, Joseph K.,Pryor, KellyAnn D.,Patel, Reshma A.,He, Huaibing,Lyons, Kathryn A.,Thornberry, Nancy A.,Weber, Ann E.
, p. 3373 - 3377 (2007)
A series of β-aminoamides bearing triazolopiperazines has been prepared and evaluated as potent, selective, orally active dipeptidyl peptidase IV (DPP-4) inhibitors. Efforts at optimization of the β-aminoamide series, which ultimately led to the discovery