94530-07-1

Basic information

• Product Name: 1,4,7-Tritosyl-1,4,7,10-tetraazacyclododecane
• Synonyms: 1,4,7-Tris(4-methylphenylsulfonyl)-1,4,7,10-tetraazacyclododecane;1,4,7-Tritosyl-1,4,7,10-tetraazacyclododecane;1,4,7-Tris(p-tolylsulfonyl)-1,4,7,10-tetrazacyclododecane
• CAS NO: 94530-07-1
• Molecular Formula: C₂₉H₃₈N₄O₆S₃
• Molecular Weight: 634.83022
• Mol File: 94530-07-1.mol

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 1,4,7-Tritosyl-1,4,7,10-tetraazacyclododecane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4,7-Tritosyl-1,4,7,10-tetraazacyclododecane(94530-07-1)
• EPA Substance Registry System: 1,4,7-Tritosyl-1,4,7,10-tetraazacyclododecane(94530-07-1)

Safety Data

• Hazardous Substances Data: 94530-07-1(Hazardous Substances Data)

Usage

Uses

Used in Coordination Chemistry:
1,4,7-Tritosyl-1,4,7,10-tetraazacyclododecane is used as a ligand for forming stable complexes with metal ions, which is crucial in coordination chemistry. The high charge and cyclic nature of the molecule contribute to the stability and versatility of these complexes.
Used in Catalysis:
The complexes formed by 1,4,7-Tritosyl-1,4,7,10-tetraazacyclododecane with metal ions are utilized in catalysis. The ligand's ability to chelate metal ions enhances the catalytic activity and selectivity of the resulting complexes in various chemical reactions.
Used in Bioinorganic Chemistry:
1,4,7-Tritosyl-1,4,7,10-tetraazacyclododecane and its metal complexes find applications in bioinorganic chemistry. They can mimic the active sites of metalloenzymes or interact with biological molecules, providing insights into the role of metal ions in biological systems.
Used in Medical Imaging:
The water-solubility and stability of 1,4,7-Tritosyl-1,4,7,10-tetraazacyclododecane make it suitable for use in medical imaging. Its complexes with metal ions, particularly those of diagnostic interest like gadolinium, can be employed as contrast agents in magnetic resonance imaging (MRI) to enhance the visualization of internal body structures.
Used in Aqueous Solutions:
Due to its high water solubility, 1,4,7-Tritosyl-1,4,7,10-tetraazacyclododecane is advantageous for use in aqueous solutions. This property allows for easy manipulation and application in various chemical and biological processes that require an aqueous environment.

Upstream product

• 52601-80-6 N,N’,N”-tris(p-toluenesulfonyl)diethylenetriamine N,N-disodium salt 
• 334-22-5 N,N-bis(chloro-2-ethyl)amine 
• 294-90-6 1,4,7,10-tetraazacyclododecan 
• 98-59-9 p-toluenesulfonyl chloride 
• 56187-04-3 1,4,7-tritosyl-1,4,7-triazaheptane 
• 821-48-7 bis-(2-chloroethyl)amine hydrochloride 

Downstream Products

• 132930-12-2 1-(N,N-dimethylcarbamoylmethyl)-4,7,10-tris-(4-tolylsulphonyl)-1,4,7,10-tetraazacyclododecane 
• 155928-88-4 2-bromo-1-(4,7,10-tritosyl-1,4,7,10-tetraazacyclododec-1-yl)ethan-1-one 
• 133587-10-7 1,1'-<1,3-phenylenebis(methylene)>bis<1,4,7,10-tetraazacyclododecane> 
• 133587-11-8 1-[4-(1,4,7,10-tetraazacyclododecan-1-ylmethyl)benzyl]-1,4,7,10-tetraazacyclododecane 
• 155928-90-8 1,4,8-tritosyl-11-<2-(4,7,10-tritosyl-1,4,7,10-tetraazacyclododec-1-yl)ethyl>-1,4,8,11-tetraazacyclotetradecane 
• 155928-89-5 1-(4,7,10-tritosyl-1,4,7,10-tetraazacyclododec-1-yl)-2-(4,8,11-tritosyl-1,4,8,11-tetraazacyclotetradec-1-yl)ethan-1-one 

Relevant articles and documents

SYNTHESIS AND CHARACTERIZATION OF A NOVEL PHTHALOCYANINATE SUBSTITUTED WITH EIGHT TETRAAZAMACROCYCLES AND ITS NONANUCLEAR COMPLEXES

A novel copper(II) phthalocyaninate substituted with eight 12-membered tetraazamacrocycles and its nonanuclear (Ni(II), Cu(II), Co(II) and Zn(II)) complexes were synthesized and characterized by elemental analysis, and IR and UV/VIS, and TGA.

Regioselective synthesis of 1,7-diprotected 1,4,7,10-tetraazacyclododecane and preparation of a dialcohol dicarboxylic macrocyclic ligand

The reaction of 1,4,7,10-tetraazacyclododecane with p-toluenesulfonyl chloride in pyridine or with diethyl phosphite and CCl4 in a water/CH2Cl2 mixture yields selectively the 1,7-diprotected regioisomer.The 1,7-diprotected tetraaza cycles are interesting

Metal complexes of macrocyclic ligands. Part XXXVII. Synthesis of heteroditopic bis-macrocycles and their potential for preparing heterobinuclear metal complexes

A new and generally applicable synthetic path for the preparation of heteroditopic bis-macrocycles using tri-N-protected tetraazacycloalkanes as building blocks and bromoacetyl bromide as bridging reagent is described. In the first step, bromoacetyl bromi

Structure and Solution Stability of Indium and Gallium Complexes of 1,4,7-Triazacyclononanetriacetate and of Yttrium Complexes of 1,4,7,10-Tetraazacyclododecanetetraacetate and Related Ligands: Kinetically Stable Complexes for Use in Imaging and Radioimmu

Of the four triazacycloalkanetriacetic acids screened for their ability to bind 111In, triazacyclononanetriacetate bound indium most quickly and formed a complex whose dissociation as a function of pD was monitored by 13C NMR spectrometry using a labelled

Synthesis of 1,2-Bis(1,4,7,10-tetra-azadodecanyl)ethane, a Double-ring Fully Saturated Macrocycle containing 12-Membered Tetra-aza Subunits

The title compound, a fully saturated bimacrocycle (1), has been obtained through a procedure involving the protection of all but one of the amino nitrogen atoms of each tetra-aza ring which are then bridged by an ethylenic segment; (1) behaves as a dinucleating ligand, forming a dicopper(II) complex in which there is a weak ferromagnetic interaction between the metal atoms.