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(Z)-3-(2-Hydroxybutylidene)isobenzofuran-1(3H)-one, also known as 3-Hydroxybutylidene-3,4-dihydro-isocoumarin, is an organic compound with a molecular formula of C13H12O3. It is classified as a lactone, which is a type of cyclic ester. (Z)-3-(2-Hydroxybutylidene)isobenzofuran-1(3H)-one is recognized for its potential biological activities, including antibacterial, antifungal, and anti-inflammatory properties. Its unique structural features make it a significant building block in the fields of organic and medicinal chemistry, and it holds promise for the study and development of novel drug molecules.

94530-83-3

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94530-83-3 Usage

Uses

Used in Pharmaceutical Synthesis:
(Z)-3-(2-Hydroxybutylidene)isobenzofuran-1(3H)-one is used as a key intermediate in the synthesis of various pharmaceutical and natural products. Its unique structure and reactivity contribute to the development of new therapeutic agents.
Used in Organic Chemistry:
In the field of organic chemistry, (Z)-3-(2-Hydroxybutylidene)isobenzofuran-1(3H)-one is used as a building block for the creation of complex organic molecules. Its versatility in reactions allows for the synthesis of a wide range of compounds.
Used in Medicinal Chemistry:
(Z)-3-(2-Hydroxybutylidene)isobenzofuran-1(3H)-one is used as a structural component in the design and development of novel drug molecules. Its potential biological activities, such as antibacterial, antifungal, and anti-inflammatory properties, make it a valuable asset in the search for new treatments for various diseases.
Used in the Study of Biological Activities:
(Z)-3-(2-Hydroxybutylidene)isobenzofuran-1(3H)-one is used in research as a model to study its antibacterial, antifungal, and anti-inflammatory properties. Understanding these activities can lead to the development of new drugs targeting these specific biological functions.
Used in Drug Delivery Systems:
Similar to gallotannin, (Z)-3-(2-Hydroxybutylidene)isobenzofuran-1(3H)-one may also be employed in drug delivery systems to improve its bioavailability and therapeutic outcomes. The development of novel carriers, such as organic and metallic nanoparticles, could enhance the compound's delivery and efficacy.

Check Digit Verification of cas no

The CAS Registry Mumber 94530-83-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,5,3 and 0 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 94530-83:
(7*9)+(6*4)+(5*5)+(4*3)+(3*0)+(2*8)+(1*3)=143
143 % 10 = 3
So 94530-83-3 is a valid CAS Registry Number.

94530-83-3Downstream Products

94530-83-3Relevant academic research and scientific papers

Regioselective synthesis of natural and unnatural (Z)-3-(1- alkylidene)phthalides and 3-substituted isocoumarins starting from methyl 2- hydroxybenzoates

Bellina, Fabio,Ciucci, Donatella,Vergamini, Piergiorgio,Rossi, Renzo

, p. 2533 - 2545 (2007/10/03)

(Z)-3-(1-Alkylidene)phthalides and 3-substituted isocoumarins, which include compounds bearing a substituent on their benzene ring, have been selectively and efficiently synthesized by a new protocol which involves: (i) the conversion of methyl 2-hydroxybenzoates into the corresponding nonaflates; (ii) Pd-catalyzed alkynylation reactions of these derivatives; (iii) the conversion of the so obtained methyl 2-(1-alkynyl)benzoates into the corresponding carboxylic acids followed by a transition metal-catalyzed heteroannulation reaction. This procedure has been used to prepare either natural products such as senkyunolide B, senkyunolide C, 3-propylisocoumarin and artemidin, or the MEM-ether of senkyunolide E. The regioselectivity of the transition metal-catalyzed cyclization reactions of 2-(1-alkynyl)benzoic acids has proven to be affected either by the catalyst used or the type of 1- alkynyl group present in these carboxylic acids. (C) 2000 Elsevier Science Ltd.

A new and convenient synthesis of (Z)-3-(2-hydroxybutylidene)phthalide

Li, Shaobai,Yan, Fulin,Wang, Zhiwei,Li, Yulin

, p. 1178 - 1179 (2007/10/02)

A new, convenient and high yield synthesis of (Z)-3-(2-hydroxybutylidene)phthalide (1) is described starting from (Z)-3-butylidenephthalide (2).

Synthesis of (Z)-3-(2-hydroxybutylidene)phthalide

Wang,Li,Yan,Li

, p. 3135 - 3139 (2007/10/02)

The first synthesis of (Z)-3-(2-hydroxybutylidene)phthalide (1) is described, starting from phthalic anhydride (2). The key step in the synthesis is the condensation of the kinetic lithium enolate of butanone with 2.

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