278175-48-7

Basic information

• Product Name: methyl 2-(perfluoro-1-butanesulfonyloxy)benzoate
• Synonyms: methyl 2-(perfluoro-1-butanesulfonyloxy)benzoate
• CAS NO: 278175-48-7
• Molecular Weight: 434.236
• Mol File: 278175-48-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl 2-(perfluoro-1-butanesulfonyloxy)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(perfluoro-1-butanesulfonyloxy)benzoate(278175-48-7)
• EPA Substance Registry System: methyl 2-(perfluoro-1-butanesulfonyloxy)benzoate(278175-48-7)

Safety Data

• Hazardous Substances Data: 278175-48-7(Hazardous Substances Data)

Upstream product

• 375-72-4 Nonafluorobutanesulfonyl fluoride 
• 119-36-8 methyl salicylate 
• 2991-84-6 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonyl chloride 

Downstream Products

• 278175-55-6 methyl 2-(3-hydroxy-1-pentynyl)benzoate 
• 278175-60-3 2-[3-(2-methoxyethoxymethoxy)-1-pentynyl]benzoic acid 
• 278175-59-0 (E)-2-(3-hexen-1-ynyl)benzoic acid 
• 173414-53-4 2-(1-pentynyl)-benzoic acid 
• 94530-83-3 senkyunolide E 
• 29428-84-0 trans-artemidin 
• 105279-16-1 (Z)-3-(4-chlorophenyl)methylidenephthalide 
• 35708-19-1 Methyl N-phenylanthranilate 
• 33577-99-0 2-ethynyl-benzoic acid methyl ester 
• 33578-05-1 methyl 2-(phenylethynyl)benzoate 
• 278175-56-7 methyl (E)-2-(3-hexen-1-ynyl)benzoate 
• 278175-54-5 methyl 2-[3-(2-methoxyethoxymethoxy)-1-pentynyl]benzoate 
• 90584-93-3 methyl 2-(pent-1-yn-1-yl)benzoate 

Relevant articles and documents

Palladium-Catalyzed Amination of Aryl Nonaflates

The first detailed study of the palladium-catalyzed amination of aryl nonaflates is reported. Use of ligands 2-4 and 6 allows for the catalytic amination of electron-rich and -neutral aryl nonaflates with both primary and secondary amines. With use of Xantphos 5, the catalytic amination of a variety of functionalized aryl nonaflates resulted in excellent yields of anilines; even 2-carboxymethyl aryl nonaflate is effectively coupled with a primary alkylamine. Moderate yields were obtained when coupling halo-aryl nonaflates with a variety of amines, where in most cases the aryl nonaflate reacted in preference to the aryl halide. Overall, aryl nonaflates are an effective alternative to triflates in palladium-catalyzed C-N bond-forming processes due to their increased stability under the reaction conditions.

Regioselective synthesis of natural and unnatural (Z)-3-(1- alkylidene)phthalides and 3-substituted isocoumarins starting from methyl 2- hydroxybenzoates

(Z)-3-(1-Alkylidene)phthalides and 3-substituted isocoumarins, which include compounds bearing a substituent on their benzene ring, have been selectively and efficiently synthesized by a new protocol which involves: (i) the conversion of methyl 2-hydroxybenzoates into the corresponding nonaflates; (ii) Pd-catalyzed alkynylation reactions of these derivatives; (iii) the conversion of the so obtained methyl 2-(1-alkynyl)benzoates into the corresponding carboxylic acids followed by a transition metal-catalyzed heteroannulation reaction. This procedure has been used to prepare either natural products such as senkyunolide B, senkyunolide C, 3-propylisocoumarin and artemidin, or the MEM-ether of senkyunolide E. The regioselectivity of the transition metal-catalyzed cyclization reactions of 2-(1-alkynyl)benzoic acids has proven to be affected either by the catalyst used or the type of 1- alkynyl group present in these carboxylic acids. (C) 2000 Elsevier Science Ltd.