945324-74-3

Upstream product

• 91-56-5 indole-2,3-dione 
• 5471-20-5 2-amino-N-benzylbenzamide 
• 118-48-9 isatoic anhydride 
• 100-46-9 benzylamine 

Relevant academic research and scientific papers

V-N-C catalysts anchored to mesoporous Al-SBA-15 with tailorable pore sizes for the synthesis of spirooxindole dihydroquinazolinones derivatives

Heterogeneous nanoscale catalyst was successfully synthesized via anchoring of V-bis(2-aminobenzamide) complex on the Al-SBA-15. This modified mesoporous was identified by several characterization techniques, such as X-ray diffraction, field emission-scanning electron microscopy, Fourier transform-infrared, Brunauer–Emmett–Teller and transmission electron microscopy. V-Bis(2-aminobenzamide)@Al-SBA-15 was found to be an efficient heterogeneous catalyst for the rapid and desirable synthesis of various spirooxindole dihydroquinazolinones derivatives. In addition, the heterogeneous nanocatalyst was chemically stabilized in organic and aqueous solutions as well as can be expeditiously reused for at least seven cycles without a significant loss in catalytic activity.

Access to enhanced catalytic core-shell CuO-Pd nanoparticles for the organic transformations

This paper describes the biosynthesis of core-shell CuO-Pd nanoparticles with the aid of a Cyperus rotundus rhizome extract. The crystallinity, surface chemistry, morphology and thermal properties of the synthesized nanoparticles were characterized by X-ray diffraction, X-ray photoelectron spectroscopy, transmission electron microscopy, and thermogravimetric analysis. The nanoparticles with Pd covered by a CuO enriched shell showed enhanced catalytic performance for organic transformations to synthesize 2,3-dihydroquinazolin-4(1H)-ones, spirooxindoles, and chromenylpyrimidin-2,4-diones in excellent yield. Moreover, the nanocatalyst can be recycled effectively for five consecutive reactions without significant loss of catalytic activity.

Ethylenediamine diacetate-catalyzed three-component reaction for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones and their spirooxindole derivatives

Ethylenediamine diacetate (EDDA)-catalyzed one-pot syntheses of biologically interesting 2,3-dihydroquinazolin-4(1H)-ones and their spirooxindole derivatives from isatoic anhydride, amines, and benzaldehydes or isatins via a three-component condensation in aqueous media have been described. This method is of great value because of high yields and ease of handling.

An efficient and convenient protocol for the synthesis of novel 1′H-spiro[isoindoline-1,2′-quinazoline]-3,4′(3′H)-dione derivatives

An efficient and direct procedure for the synthesis of novel spiro[isoindoline-1,2′-quinazoline]-3,4′(3′H)-dione derivatives is described. The process employs a condensation reaction of 2-aminobenzamides and isatins in the presence of a catalytic amount o

A regioselective three-component reaction for synthesis of novel 1′H-spiro[isoindoline-1,2′-quinazoline]-3,4′(3′H)-dione derivatives

A ring opening and regioselective three-component reaction of isatoic anhydride, isatins, and aromatic or aliphatic primary amines in the presence of catalytic amount of KAl(SO4)2·12H2O (alum) to yield a novel series of 1′H-spiro[isoindoline-1,2′-quinazoline]-3,4′(3′H)-dione is described.