945383-09-5Relevant articles and documents
METHOD FOR PRODUCING NUCLEOSIDE DERIVATIVE
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, (2020/05/13)
PROBLEM TO BE SOLVED: To provide a practical method for producing a nucleoside derivative that is applied to RNA pharmaceuticals or the like. SOLUTION: The present invention provides a method for producing a nucleotide derivative represented by a compound
Five- and six-membered conformationally locked 2′,4′- carbocyclic ribo-thymidines: Synthesis, structure, and biochemical studies
Srivastava, Puneet,Barman, Jharna,Pathmasiri, Wimal,Plashkevych, Oleksandr,Wenska, Malgorzata,Chattopadhyaya, Jyoti
, p. 8362 - 8379 (2008/02/08)
Two unusual reactions involving the 5-hexenyl or the 6-heptenyl radical cyclization of a distant double bond at C4′ and the radical center at C2′ of the ribofuranose ring of thymidine have been used as key steps to synthesize North-type conformationally c