945492-88-6

Basic information

• Product Name: C₂₃H₄₁N₃O₅SSi
• CAS NO: 945492-88-6
• Molecular Weight: 499.747
• Mol File: 945492-88-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₃H₄₁N₃O₅SSi(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₄₁N₃O₅SSi(945492-88-6)
• EPA Substance Registry System: C₂₃H₄₁N₃O₅SSi(945492-88-6)

Safety Data

• Hazardous Substances Data: 945492-88-6(Hazardous Substances Data)

Upstream product

• 162007-07-0 methyl (2S)-(tert-butoxycarbonylamino)-5-hydroxypentanoate 
• 59279-58-2 N^α-tert-butyloxycarbonyl-γ-benzyloxycarbonyl-L-glutamic acid methyl ester 
• 1694-92-4 2-Nitrobenzenesulfonyl chloride 
• 13154-24-0 triisopropylsilyl chloride 
• 56-86-0 L-glutamic acid 
• 945492-90-0 (S)-2-(N-Boc-amino)-5-(triisopropylsilyloxy)pentan-1-ol 
• 945492-91-1 (S)-N¹-allyl-N²-Boc-N¹-(o-nitrobenzenesulfonyl)-5-(triisopropylsilyloxy)pentane-1,2-diamine 
• 65118-17-4 N-allyl-o-nitrobenzenesulfonamide 
• 72086-72-7 N-tert-butoxycarbonylglutamic acid methyl ester 
• 13574-13-5 Boc-Glu(OBzl)-OH 

Downstream Products

• 945492-93-3 (2R,S)-2-[N-allyl-3-(4-benzyloxyphenyl)propanamido]-N-[(2S)-1-(N-allyl-o-nitrophenylsulfonamido)-5-triisopropylsilyloxypentan-2-yl]-5-triisopropylsilyloxypentanamide 
• 945492-95-5 (2S)-2-[N-allyl-3-(4-benzyloxyphenyl)acetamido]-N-[(2S)-1-(N-allyl-o-nitrophenylsulfonamido)-5-triisopropylsilyloxypentan-2-yl]-5-triisopropylsilyloxypentanamide 
• 945492-96-6 (2R)-2-[N-allyl-3-(4-benzyloxyphenyl)acetamido]-N-[(2S)-1-(N-allyl-o-nitrophenylsulfonamido)-5-triisopropylsilyloxypentan-2-yl]-5-triisopropylsilyloxypentanamide 
• 945492-99-9 (2S,5S,6E)-2,5-bis[3-(triisopropylsilyloxy)propyl]-1-[3-(4-benzyloxyphenyl)propionyl]-7-(o-nitrobenzenesulfonyl)-1,4,7-triazacycloundec-9-en-3-one 
• 945493-00-5 (2R,5S,6E)-2,5-bis[3-(triisopropylsilyloxy)propyl]-1-[3-(4-benzyloxyphenyl)propionyl]-7-(o-nitrobenzenesulfonyl)-1,4,7-triazacycloundec-9-en-3-one 
• 945493-03-8 (2S,5S,6E)-2,5-bis[3-(triisopropylsilyloxy)propyl]-1-(4-benzyloxyphenylacetyl)-7-(o-nitrobenzenesulfonyl)-1,4,7-triazacycloundec-9-en-3-one 
• 945493-04-9 (2R,5S,6E)-2,5-bis[3-(triisopropylsilyloxy)propyl]-1-(4-benzyloxyphenylacetyl)-7-(o-nitrobenzenesulfonyl)-1,4,7-triazacycloundec-9-en-3-one 
• 945493-07-2 (2S,5S,6E)-2,5-bis[3-(triisopropylsilyloxy)propyl]-1-[3-(4-benzyloxyphenyl)propionyl]-7-(2-naphthylacetyl)-1,4,7-triazacycloundec-9-en-3-one 

Relevant articles and documents

Design and synthesis of all diastereomers of cyclic pseudo-dipeptides as mimics of cyclic CXCR4 pentapeptide antagonists

The four diastereomers of 2,5-bis[(3-guanidino)propyl]-1-[3-(4- hydroxyphenyl)propionyl]-7-(2-naphthylacetyl)-1,4,7-triazacycloundec-9-en-3-one (54-57) and of 2,5-bis[(3-guanidino)propyl]-1-(4-hydroxyphenylacetyl)-7-(2- naphthylacetyl)-1,4,7-triazacycloundec-9-en-3-one (58-61) were synthesized by a divergent methodology from l- and d-glutamic acids. The 11-membered ring core was made by ring closing metathesis of linear bis(allylamines), and the guanidyl functions were introduced by a simultaneous double Mitsunobu reaction using bis(Boc)guanidine. These compounds were designed to mimic cyclic pentapeptide FC131 (c[Gly-d-Tyr-Arg-Arg-Nal]). The Royal Society of Chemistry.