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59279-58-2

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59279-58-2 Usage

General Description

BOC-GLU(OBZL)-OME, also known as tert-butyl (2-(((benzyloxy)carbonyl)amino)-3-(benzyloxy)propanoate, is a chemical compound used in the field of organic chemistry. BOC-GLU(OBZL)-OME is useful in peptide synthesis. Its molecular formula is C22H29NO6, signifying it contains 22 carbon atoms, 29 hydrogen atoms, 1 nitrogen atom, and 6 oxygen atoms. The BOC in the name refers to the tert-butoxycarbonyl protecting group, the GLU refers to glutamic acid residue, OBZL refers to the benzyl ester protecting group, and OME refers to the methoxy group. These specific groups are utilized for their ability to undergo specific reactions while preventing other parts of the molecule from reacting.

Check Digit Verification of cas no

The CAS Registry Mumber 59279-58-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,2,7 and 9 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 59279-58:
(7*5)+(6*9)+(5*2)+(4*7)+(3*9)+(2*5)+(1*8)=172
172 % 10 = 2
So 59279-58-2 is a valid CAS Registry Number.

59279-58-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-O-benzyl 1-O-methyl (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanedioate

1.2 Other means of identification

Product number -
Other names (2S)-2-tert-butoxycarbonylaminopentanedioic acid 5-benzyl ester 1-methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:59279-58-2 SDS

59279-58-2Relevant articles and documents

An irreversible inhibitor of peptidyl-prolyl cis/trans isomerase Pin1 and evaluation of cytotoxicity

Ieda, Naoya,Itoh, Kaoru,Inoue, Yasumichi,Izumiya, Yusuke,Kawaguchi, Mitusyasu,Miyata, Naoki,Nakagawa, Hidehiko

, p. 353 - 356 (2019)

Pin1 (protein interacting with never in mitosis A-1) is a member of the peptidyl prolyl isomerase (PPIase) family, and catalyzes cis-trans isomerization of pThr/Ser-Pro amide bonds. Because Pin1 is overexpressed in various cancer cell lines and promotes c

Synthesis of l -Kynurenine and Homo- l -Kynurenine via an Aza-Fries Rearrangement

Bonilla-Reyes, Edgar,Sánchez-Carrillo, Adrian,Vázquez, Alfredo

, p. 3473 - 3479 (2020/09/15)

l -Kynurenine, a non-proteinogenic amino acid, is the primary metabolite of tryptophan via the kynurenine pathway. Kynurenine is involved in a variety of biological processes occurring in the human body, notably in the central nervous system. Thus, the st

Oxadiazole-Based Cell Permeable Macrocyclic Transition State Inhibitors of Norovirus 3CL Protease

Damalanka, Vishnu C.,Kim, Yunjeong,Alliston, Kevin R.,Weerawarna, Pathum M.,Galasiti Kankanamalage, Anushka C.,Lushington, Gerald H.,Mehzabeen, Nurjahan,Battaile, Kevin P.,Lovell, Scott,Chang, Kyeong-Ok,Groutas, William C.

, p. 1899 - 1913 (2016/03/22)

Human noroviruses are the primary causative agents of acute gastroenteritis and a pressing public health burden worldwide. There are currently no vaccines or small molecule therapeutics available for the treatment or prophylaxis of norovirus infections. Norovirus 3CL protease plays a vital role in viral replication by generating structural and nonstructural proteins via the cleavage of the viral polyprotein. Thus, molecules that inhibit the viral protease may have potential therapeutic value. We describe herein the structure-based design, synthesis, and in vitro and cell-based evaluation of the first class of oxadiazole-based, permeable macrocyclic inhibitors of norovirus 3CL protease.

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