945534-11-2Relevant academic research and scientific papers
OXEPANE NUCLEOSIDES AND OLIGONUCLEOTIDES, USES THEREOF AND METHODS OF MAKING THE SAME
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Page/Page column 39, (2010/11/30)
The present invention provides oxepane nucleosides, oxepane nucleotides, modified oxepane nucleotides, oligonucleotides, methods for making and uses for modulating gene expression. The oxepane nucleoside having formula I : wherein B is a heterocyclic base
Oxepane nucleic acids: Synthesis, characterization, and properties of oligonucleotides bearing a seven-membered carbohydrate ring
Sabatino, David,Damha, Masad J.
, p. 8259 - 8270 (2008/02/09)
The synthesis and properties of oxepane nucleic acids (ONAs) are described. ONAs are sugar - phosphate oligomers in which the pentofuranose ring of DNA and RNA is replaced with a seven-membered (oxepane) sugar ring. The oxepane nucleoside monomers were pr
