945534-35-0

Upstream product

• 1026316-05-1 C₃₈H₄₇N₅O₇ 
• 945534-33-8 Boc-2'-formyl-D-tryptophan 
• 1094779-54-0 (2S)-6-{[(benzyloxy)carbonyl]amino}-2-[(4R)-4-[(tert-butoxycarbonyl)amino]-3-oxo-3,4,5,10-tetrahydroazepino[3,4-b]indol-2(1H)-yl]hexanoic acid 
• 100-46-9 benzylamine 
• 246869-37-4 H2N-L-Lys(ε-Cbz)-CONHCH2Ph 

Downstream Products

• 945534-38-3 benzyl (5R)-6-(benzylamino)-6-oxo-5-[(4R)-3-oxo-4-[(phenylacetyl)amino]-3,4,5,10-tetrahydroazepino[3,4-b]indol-2(1H)-yl]hexylcarbamate 
• 945534-39-4 benzyl (5R)-6-(benzylamino)-5-[(4R)-4-[(3,3-diphenylpropanoyl)amino]-3-oxo-3,4,5,10-tetrahydroazepino[3,4-b]indol-2(1H)-yl]-6-oxohexylcarbamate 

Relevant academic research and scientific papers

Highly potent 4-amino-indolo[2,3-c]azepin-3-one-containing somatostatin mimetics with a range of sst receptor selectivities

The synthesis, biological evaluation, and conformational analysis of 4-amino-indolo[2,3-c]azepin-3-one (Aia)- containing SRIF mimetics are reported. Different subtype selectivities are observed depending on the N- and C-terminal substituents of the D-Aia-

New sst4/5-selective somatostatin peptidomimetics based on a constrained tryptophan scaffold

The synthesis and biological evaluation of four peptidomimetic analogs of somatostatin based on a constrained Trp residue, 3-amino-indolo[2,3-c]azepin-2- one (Aia), are reported. It is shown that dipeptidomimetics with a D-Aia-Lys sequence, functionalized