945541-23-1

Basic information

• Product Name: 2-(2,2-dibromoethenyl)-1-methoxy-3-methylbenzene
• Synonyms: 2-(2,2-dibromoethenyl)-1-methoxy-3-methylbenzene
• CAS NO: 945541-23-1
• Molecular Weight: 305.997
• Mol File: 945541-23-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-(2,2-dibromoethenyl)-1-methoxy-3-methylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,2-dibromoethenyl)-1-methoxy-3-methylbenzene(945541-23-1)
• EPA Substance Registry System: 2-(2,2-dibromoethenyl)-1-methoxy-3-methylbenzene(945541-23-1)

Safety Data

• Hazardous Substances Data: 945541-23-1(Hazardous Substances Data)

Upstream product

• 558-13-4 carbon tetrabromide 
• 54884-55-8 2-methoxy-6-methyl-benzaldehyde 

Downstream Products

• 1308401-07-1 C₁₁H₁₀O₃ 
• 1308400-96-5 3-(2-methoxy-6-methylphenyl)propynoic acid benzylnaphthalen-2-ylamide 
• 1308401-00-4 3-(2-methoxy-6-methylphenyl)propynoic acid benzyl(3,5-dimethoxyphenyl)amide 
• 1174514-48-7 C₁₂H₁₂O₃ 
• 1421187-03-2 2-ethynyl-1-methoxy-3-methylbenzene 
• 1421187-17-8 1-bromo-3-methoxy-2-((2-methoxy-6-methylphenyl)ethynyl)benzene 
• 1421187-15-6 1-bromo-1-methoxy-3-((2-methoxy-6-methylphenyl)ethynyl)benzene 
• 1421187-20-3 1-cyclopentenyl-3-methoxy-2-((2-methoxy-6-methylphenyl)ethynyl)benzene 
• 1421186-86-8 2-((2-cyclohexenylphenyl)ethynyl)-1-methoxy-3-methylbenzene 
• 1421186-82-4 2-cyclopentenyl-1-methoxy-3-((2-methoxy-6-methylphenyl)ethynyl)benzene 
• 1421186-80-2 1-((3',5'-dimethoxybiphenyl-2-yl)ethynyl)-2-methylnaphthalene 
• 1421187-05-4 2-((2-bromophenyl)ethynyl)-1-methoxy-3-methylbenzene 

Relevant articles and documents

Palladium(II)-catalyzed asymmetric cycloisomerization of enynes for axially chiral biaryl construction

Palladium(II)-catalyzed asymmetric cycloisomerization of enynes with (R)-binap gave axially chiral biaryls with up to 99%ee. The reactivity and enantioselectivity depended on the nature and position of substituent of the arene ring. The enynes with ortho methoxy arene at alkyne terminus gave chiral biaryls with good enantioselectivity.

Palladium-catalyzed enantioselective intramolecular hydroarylation of alkynes to form axially chiral 4-aryl 2-quinolinones

A long-awaited asymmetric version of the intramolecular hydroarylation of alkynes to form fused ring systems has been developed. A cationic palladium(II)/(S)-xyl-H8-binap complex was used to catalyze an enantioselective hydroarylation of alkynes at room temperature to furnish axially chiral 4-aryl 2-quinolinone derivatives in good yields with good enantioselectivity (see scheme; Bn=benzyl).