1308400-96-5Relevant articles and documents
Palladium-catalyzed enantioselective intramolecular hydroarylation of alkynes to form axially chiral 4-aryl 2-quinolinones
Shibuya, Tetsuro,Shibata, Yu,Noguchi, Keiichi,Tanaka, Ken
, p. 3963 - 3967 (2011/06/24)
A long-awaited asymmetric version of the intramolecular hydroarylation of alkynes to form fused ring systems has been developed. A cationic palladium(II)/(S)-xyl-H8-binap complex was used to catalyze an enantioselective hydroarylation of alkynes at room temperature to furnish axially chiral 4-aryl 2-quinolinone derivatives in good yields with good enantioselectivity (see scheme; Bn=benzyl).