945551-93-9

Basic information

• Product Name: (1R,2S)-N,N'-bis[(1S)-2-hydroxy-1-phenyl-methylethyl]-3,3-dimethyl-1,2-cyclopropanedicarboxamide
• Synonyms: (1R,2S)-N,N'-bis[(1S)-2-hydroxy-1-phenyl-methylethyl]-3,3-dimethyl-1,2-cyclopropanedicarboxamide
• CAS NO: 945551-93-9
• Molecular Weight: 424.54
• Mol File: 945551-93-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2S)-N,N'-bis[(1S)-2-hydroxy-1-phenyl-methylethyl]-3,3-dimethyl-1,2-cyclopropanedicarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S)-N,N'-bis[(1S)-2-hydroxy-1-phenyl-methylethyl]-3,3-dimethyl-1,2-cyclopropanedicarboxamide(945551-93-9)
• EPA Substance Registry System: (1R,2S)-N,N'-bis[(1S)-2-hydroxy-1-phenyl-methylethyl]-3,3-dimethyl-1,2-cyclopropanedicarboxamide(945551-93-9)

Safety Data

• Hazardous Substances Data: 945551-93-9(Hazardous Substances Data)

Upstream product

• 3182-95-4 L-Phenylalaninol 
• 119908-76-8 cis-3,3-dimethylcyclopropane-1,2-dicarbonyl dichloride 

Downstream Products

• 945551-89-3 (1R,2S)-1,2-bis[4(S)-benzyloxazolin-2-yl]-3,3-dimethylcyclopropane 

Relevant articles and documents

Catalytic asymmetric nitroaldol (Henry) reactions with copper(II)/ cyclopropane-based bisoxazoline complexes

A series of cyclopropane-based bisoxazolines were synthesized from (R)- and (S)-amino alcohols, and applied to copper-catalyzed enantioselective nitroaldol reactions between nitromethane and various aldehydes. The reactions generated β-hydroxy nitroalkanes in high yields (97%) and with good enantioselectivities (up to 87% ee). The effects of the oxazoline stereocenters constructed in the Henry reactions were also studied. 2012 Elsevier Ltd.