945593-07-7Relevant academic research and scientific papers
Gold catalysis in stereoselective natural product synthesis: (+)-linalool oxide, (-)-isocyclocapitelline, and (-)-isochrysotricine
Volz, Frank,Wadman, Sipke H.,Hoffmann-R?der, Anja,Krause, Norbert
experimental part, p. 1902 - 1910 (2009/06/20)
A stereoselective synthesis of the tetrahydrofuran-containing natural products (2S,5R)-(+)-linalool oxide (1), (-)-isocyclocapitelline (2), and (-)-isochrysotricine (3) is reported. Key steps are the copper-mediated SN2′-substitution of proparg
Golden opportunities in natural product synthesis: First total synthesis of (-)-isocyclocapitelline and (-)-isochrysotricine by gold-catalyzed allene cycloisomerization
Volz, Frank,Krause, Norbert
, p. 1519 - 1521 (2008/02/05)
The first enantioselective total syntheses of the β-carboline alkaloids (-)-isochrysotricine (1) and (-)-isocyclocapitelline (2) are reported which confirm the absolute configuration of these natural products. Key steps are the copper-mediated SN/su
