945606-75-7

Basic information

• Product Name: benzyl 6-N-Boc-adenin-9-ylacetate
• Synonyms: benzyl 6-N-Boc-adenin-9-ylacetate
• CAS NO: 945606-75-7
• Molecular Weight: 383.407
• Mol File: 945606-75-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: benzyl 6-N-Boc-adenin-9-ylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 6-N-Boc-adenin-9-ylacetate(945606-75-7)
• EPA Substance Registry System: benzyl 6-N-Boc-adenin-9-ylacetate(945606-75-7)

Safety Data

• Hazardous Substances Data: 945606-75-7(Hazardous Substances Data)

Upstream product

• 5437-45-6 Benzyl bromoacetate 
• 66224-66-6 adenine 
• 530-62-1 1,1'-carbonyldiimidazole 
• 75-65-0 tert-butyl alcohol 
• 183181-27-3 benzyl 2-(6-amino-9H-purin-9-yl)acetate 

Downstream Products

• 186046-99-1 (N⁶-Boc-N⁹-adeninyl)acetic acid 

Relevant articles and documents

Optimized Synthesis of Fmoc/Boc-Protected PNA Monomers and their Assembly into PNA Oligomers.

Continuous advancement of application of peptide nucleic acid (PNA) oligomers encouraged exploration of rapid and efficient synthesis of PNA monomers and oligomers. Among the PNA monomers developed, only a few are commonly used in automated PNA synthesis.

Expanding the scope of PNA-encoded libraries: divergent synthesis of libraries targeting cysteine, serine and metallo-proteases as well as tyrosine phosphatases

Seven PNA-encoded combinatorial libraries targeting proteases and phosphatases with covalent reversible and irreversible mechanism-based inhibitors were prepared. The libraries were synthesized using modified PNA monomers, which dramatically increase the water solubility of the libraries in biologically relevant buffers. The libraries were shown to selectively inhibit targeted enzymes.