945608-00-4

Basic information

• Product Name: 2-phenylpyrrolo[2,3-c]pyridine-1-carboxylic acid tert-butyl ester
• Synonyms: 2-phenylpyrrolo[2,3-c]pyridine-1-carboxylic acid tert-butyl ester
• CAS NO: 945608-00-4
• Molecular Weight: 294.353
• Mol File: 945608-00-4.mol

Chemical Properties

• CAS DataBase Reference: 2-phenylpyrrolo[2,3-c]pyridine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenylpyrrolo[2,3-c]pyridine-1-carboxylic acid tert-butyl ester(945608-00-4)
• EPA Substance Registry System: 2-phenylpyrrolo[2,3-c]pyridine-1-carboxylic acid tert-butyl ester(945608-00-4)

Safety Data

• Hazardous Substances Data: 945608-00-4(Hazardous Substances Data)

Upstream product

• 449173-38-0 3-amino-4-(2-phenylethynyl)pyridine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 2922-07-8 2-phenyl-1H-pyrrolo[2,3-c]pyridine 
• 105752-11-2 4-iodopyridin-3-amine 
• 536-74-3 phenylacetylene 
• 6919-61-5 N-methoxy-N-methylbenzamide 
• 180253-66-1 3-(tert-butyloxycarbonylamino)-4-methyl-pyridine 
• 945607-67-0 [4-(2,2-dichlorovinyl)pyridin-3-yl]carbamic acid tert-butyl ester 
• 98-80-6 phenylboronic acid 

Downstream Products

• 2922-07-8 2-phenyl-1H-pyrrolo[2,3-c]pyridine 

Relevant articles and documents

Asymmetric Hydrogenation of Azaindoles: Chemo- and Enantioselective Reduction of Fused Aromatic Ring Systems Consisting of Two Heteroarenes

High enantioselectivity was achieved for the hydrogenation of azaindoles by using the chiral catalyst, which was prepared from [Ru(η3-methallyl)2(cod)] and a trans-chelating bis(phosphine) ligand (PhTRAP). The dearomative reaction exclusively occurred on the five-membered ring, thus giving the corresponding azaindolines with up to 97:3 enantiomer ratio.

2-SUBSTITUTED AZAIN DOLES AND 2 SUBSTITUTED THIENOPYRROLES, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF

The present invention relates generally to processes for the chemical synthesis of azaindole and thienopyrrole compounds, in particular azaindole and thienopyrrole compounds that are substituted at the 2-position of the azaindole or thienopyrrole ring, an

A general modular method of azaindole and thienopyrrole synthesis via Pd-catalyzed tandem couplings of gem-dichloroolefins

(Chemical Equation Presented) A palladium-catalyzed reaction of gem-dichloroolefins and a boronic acid via a tandem intramolecular C-N and intermolecular Suzuki coupling process gave corresponding substituted azaindoles or thienopyrroles. This method is a

AMIDE DERIVATIVES AND DRUGS

The present invention provides an amide derivative represented by the following formula [1]: wherein n represents 0 or 1; X represents CR4 or N; Y represents CR6 or N; Z represents CR7 or N; R1 and R2 may be the same or different and each represents hydrogen, optionally substituted alkyl, acyl, optionally substituted aryl, or an optionally substituted aromatic heterocyclic group; R4, R5, R6 and R7 may be the same or different and each represents hydrogen, halogen, hydroxy, amino, alkyl, haloalkyl, alkoxy, monoalkylamino, dialkylamino, arylalkyl, cyano, or nitro; and R3 represents optionally substituted alkylamino, optionally substituted arylamino, or optionally substituted cyclic amino, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising them as an active ingredient. The compound of the present invention is useful as a TGF-β inhibitor.