945736-77-6

Basic information

• Product Name: (1R,2S,5R)-2-Isopropyl-5-methyl-1-(1-methyl-allyl)-cyclohexanol
• Synonyms: (1R,2S,5R)-2-Isopropyl-5-methyl-1-(1-methyl-allyl)-cyclohexanol
• CAS NO: 945736-77-6
• Molecular Weight: 210.36
• Mol File: 945736-77-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2S,5R)-2-Isopropyl-5-methyl-1-(1-methyl-allyl)-cyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S,5R)-2-Isopropyl-5-methyl-1-(1-methyl-allyl)-cyclohexanol(945736-77-6)
• EPA Substance Registry System: (1R,2S,5R)-2-Isopropyl-5-methyl-1-(1-methyl-allyl)-cyclohexanol(945736-77-6)

Safety Data

• Hazardous Substances Data: 945736-77-6(Hazardous Substances Data)

Upstream product

• 10458-14-7 (2R,5S)-menthone 
• 591-97-9 1-chloro-2-butene 

Downstream Products

• 1146980-55-3 (3R,5E)-1-(benzyloxy)hept-5-en-3-ol 
• 853193-61-0 (-)-(3S,5E)-1-benzyloxyhept-5-en-3-ol 

Relevant articles and documents

1-Deoxy-5-hydroxysphingolipids as new anticancer principles: An efficient procedure for stereoselective syntheses of 2-amino-3,5-diols

(Chemical Equation Presented) Enantioselective preparation of the linear homoallylic alcohol I allows efficient formation of the 2-amino-3,5-diol moiety present in several biologically active compounds, including 1-deoxy-5- hydroxysphingosine analogue IV, which has exhibited excellent biological activity against colon cancer. The conversion of I into IV involves a sequence of enantioselective epoxidation of the O-tert-butoxycarbonyl derivative of I, followed by regioselective and stereospecific oxacyclization of II to introduce differentiated oxygens in III.