945739-16-2Relevant academic research and scientific papers
An improved ring-closing metathesis approach to fluorinated and trifluoromethylated nitrogen heterocycles
De Matteis, Valeria,Dufay, Olivier,Waalboer, Dennis C. J.,Van Delft, Floris L.,Tiebes, Joerg,Rutjes, Floris P. J. T.
, p. 2667 - 2675 (2008/02/08)
The synthesis of fluoro- and trifluoromethyl-containing N-sulfonylated nitrogen heterocycles is described. A first crucial step is a Mitsunobu functionalization of intermediate sulfonamides using commercially available unsaturated alcohols, which gives ef
