945765-83-3Relevant academic research and scientific papers
Lithium naphthalenide induced reductive selenenylation of α-cyano ketones: A regiocontrolled process for α-phenylseleno ketones and one-pot conversion into enone system
Zhu, Jia-Liang,Ko, Yen-Chun,Kuo, Chun-Wei,Shia, Kak-Shan
, p. 1274 - 1278 (2008/01/08)
An efficient procedure for the regiocontrolled synthesis of α-phenylseleno ketones has been developed, making use of the lithium naphthalenide induced reductive selenenylation of the α-cyano ketone system as a key operation. Moreover, seleno ketones thus generated in situ, upon subsequent treatment with hydrogen peroxide and acetic acid, could be further converted into the corresponding enones with a high degree of regioselectivity, presumably due to the lithium salt mediated selenoxide syn-elimination process. Georg Thieme Verlag Stuttgart.
