94583-15-0

Basic information

• Product Name: S-(4-methylphenyl) 4-nitrobenzenesulfonothioate
• CAS NO: 94583-15-0
• Molecular Formula: C₁₃H₁₁NO₄S₂
• Molecular Weight: 309.3607
• Mol File: 94583-15-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 499°C at 760 mmHg
• Flash Point: 255.6°C
• Density: 1.46g/cm³
• Vapor Pressure: 1.33E-09mmHg at 25°C
• Refractive Index: 1.668
• CAS DataBase Reference: S-(4-methylphenyl) 4-nitrobenzenesulfonothioate(CAS DataBase Reference)
• NIST Chemistry Reference: S-(4-methylphenyl) 4-nitrobenzenesulfonothioate(94583-15-0)
• EPA Substance Registry System: S-(4-methylphenyl) 4-nitrobenzenesulfonothioate(94583-15-0)

Safety Data

• Hazardous Substances Data: 94583-15-0(Hazardous Substances Data)

Upstream product

• 1041-15-2 p-nitrophenyl p-nitrobenzenethiosulfonate 
• 24398-14-9 1-[(diethylamino)sulfanyl]-4-methylbenzol 
• 1136-02-3 ethyl p-nitrobenzenethiosulfonate 
• 55099-67-7 4-Nitro-benzenethiosulfonic acid S-(2,4-dinitro-phenyl) ester 
• 456-27-9 4-nitrobenzenediazonium tetrafluoroborate 
• 106-45-6 para-thiocresol 
• 2937-05-5 4-nitrobenzenesulfonohydrazide 
• 39549-10-5 1-[(4-methylphenyl)sulfanyl]pyrrolidine-2,5-dione 
• 15959-31-6 sodium 4-nitrobenzenesulfinate 

Relevant articles and documents

Preparation method of thiosulfonate compound

The invention belongs to the field of organic synthetic chemistry, and particularly discloses a preparation method of a thiosulfonate compound. The specific preparation process comprises the following steps: taking aryl diazonium salt, sodium pyrosulfite and thiophenol/mercaptan as raw materials, taking organic dye as a photocatalyst, adding an organic solvent, and reacting for 12 hours at room temperature under the irradiation of an LED visible light lamp and nitrogen protection to generate thiosulfonate; and after the reaction is finished, adding distilled water into the reaction system, extracting the reaction liquid with ethyl acetate, concentrating the extraction liquid to obtain a crude product, and carrying out silica gel column chromatography separation on the crude product to obtain thiosulfonate. According to the method, simple and easily available sodium pyrosulfite is used as a sulfone source, cheap organic dye is used as a photocatalyst, clean light energy is used as a reaction energy source, a high-energy-consumption heating device and a metal catalyst or strong acid are not used, the reaction condition is mild, the operation is simple and convenient, and a green synthesis strategy is provided for thiosulfonate.

Synthesis method of thiosulfonate compound

The invention belongs to the field of organic synthesis, and particularly relates to a synthesis method of a thiosulfonate compound. The invention provides the synthesis method of the thiosulfonate compound. The method comprises the following steps that methanesulfonohydrazide compounds, thiophenol compounds, oxidizing agents and catalysts are dissolved into a solvent for reaction; purification isperformed to obtain the thiosulfonate compound; oxidizing agents are any one kind or several kinds of materials from tertiary butanol peroxide and catalysts are sodium iodide, potassium iodide, ammonium iodide, iodine element and tetrabutylammonium iodide. Through experiment testing, the thiosulfonate compound prepared by the technical scheme provided by the invention has the advantages that no side reaction occurs; the yield can reach 84 to 100 percent; the conversion rate is high; meanwhile, the used catalysts and catalysts are environment-friendly compounds; the environment pollution cannot be caused; the reaction temperature is low; the method is suitable for industrial mass popularization. The defects that in the prior art, the damage to the environment in the asymmetric thiosulfonates synthesis process is great, and the application to industrial production cannot be realized are overcome.

Sc(OTf)3-catalyzed synthesis of thiosulfonates in ionic liquid-water

The first example of Sc(OTf)3-catalyzed sulfenylation of sodium sulfinates with N-(organothio)succinimides in ionic liquids (ILs) and water cosolvent system was developed, achieving thiosulfonates in moderate to excellent yields. Additionally, Sc(OTf)3/ILs could be recovered easily after the reactions and reused without a significant loss in the catalytic activity. Thus, the present protocol represents an interesting complement to known methods for thiosulfonates synthesis.