945865-12-3

Upstream product

• 945865-24-7 4-bromo-3-(3-nitrophenyl)-1H-pyrazole 
• 75-03-6 ethyl iodide 

Downstream Products

• 945865-22-5 1-ethyl-3-(3-nitrophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 
• 1030610-65-1 4-[4-[1-ethyl-3-(3-nitrophenyl)-1H-pyrazol-4-yl]-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]benzaldehyde 
• 945865-14-5 3-(4-Bromo-1-ethyl-1H-pyrazol-3-yl)aniline 
• 945865-15-6 4-[1-Ethyl-3-(3-nitrophenyl)-1H-pyrazol-4-yl]-1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridine 

Relevant academic research and scientific papers

Pyrrolo [2,3,B] Pyridine Derivatives Useful As RAF Kinase Inhibitors

The present invention provides pyrrolo pyridine compounds, compositions containing the same, as well as processes for the preparation and their use as pharmaceutical agents.

Knowledge-based design of 7-azaindoles as selective B-Raf inhibitors

The synthesis of a 7-azaindole series of novel, potent B-Raf kinase inhibitors using knowledge-based design was carried out. Compound 6h exhibits not only excellent potency in both the enzyme assay (IC50 = 2.5 nM) and the cellular assay (ICsub

NOVEL COMPOUNDS

The present invention relates to azaindole derivatives, compositions and medicaments containing the same, as well as processes for the preparation and use of such compounds, compositions and medicaments. Such azaindole derivatives are potentially useful i