945933-47-1Relevant academic research and scientific papers
Synthesis and simple 18F-labeling of 3-fluoro-5-(2-(2- (fluoromethyl)thiazol-4-yl)ethynyl)benzonitrile as a high affinity radioligand for imaging monkey brain metabotropic glutamate subtype-5 receptors with positron emission tomography
Siméon, Fabrice G.,Brown, Amira K.,Zoghbi, Sami S.,Patterson, Velvet M.,Innis, Robert B.,Pike, Victor W.
, p. 3256 - 3266 (2008/02/09)
2-Fluoromethyl analogs of (3-[(2-methyl-1,3-thiazol-4yl)ethynyl]pyridine) were synthesized as potential ligands for metabotropic glutamate subtype-5 receptors (mGluR5s). One of these, namely, 3-fluoro-5-(2-(2-(fluoromethyl) thiazol-4-yl)ethynyl)benzonitri
