94602-56-9

Upstream product

• 20731-93-5 3-Phenyl-3-hexanol 
• 1530-32-1 ethyltriphenylphosphonium bromide 
• 495-40-9 propiophenone 
• 93-55-0 1-phenyl-propan-1-one 
• 252975-27-2 thiophosphoric acid S-(1-acetyl-1-phenyl-butyl) ester O,O'-diethyl ester 
• 609815-91-0 Trimethyl-((E)-1-methyl-2-phenyl-pent-1-enyloxy)-silane 
• 252975-36-3 selenophosphoric acid Se-(1-acetyl-1-phenylbutyl) ester O,O-diethyl ester 

Relevant academic research and scientific papers

Aqueous ZnCl2 Complex Catalyzed Prins Reaction of Silyl Glyoxylates: Access to Functionalized Tertiary α-Silyl Alcohols

An efficient Prins reaction of silyl glyoxylates in the presence of an aqueous ZnCl2 complex as a catalyst was developed, providing functionalized tertiary α-silyl alcohols in high yields under mild conditions. A preliminary investigation indicated that the aqueous ZnCl2 complex acted as a dual functional catalyst of Br?nsted and Lewis acid to activate the carbonyl groups of silyl glyoxylates via a dual-activation model.

Copper(i)-catalysed asymmetric allylic reductions with hydrosilanes

A copper(i)-catalysed asymmetric allylic reduction enables a regio- and stereoselective transfer of a hydride nucleophile in an SN2′-fashion onto allylic bromides. This transformation represents a conceptually orthogonal approach to allylic substitution reactions with carbon nucleophiles. A copper(i) complex based upon a chiral N-heterocyclic carbene (NHC) ligand allows for stereoselectivity reaching 99% ee. The catalyst enables a stereoconvergent reaction irrespective of the double bond configuration of the starting materials.

A new synthesis of tri- and tetrasubstituted olefins based on thio- and selenophosphates

Stereoselective synthesis of tri- and tetrasubstituted functionalized olefins and new phosphates bearing functionalized cyclic substituent has been developed using thiophosphates and selenophosphates as key intermediates.