946076-26-2

Basic information

• Product Name: N-allyl-3-methoxybenzenesulfonamide
• Synonyms: N-allyl-3-methoxybenzenesulfonamide
• CAS NO: 946076-26-2
• Molecular Weight: 227.284
• Mol File: 946076-26-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-allyl-3-methoxybenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-allyl-3-methoxybenzenesulfonamide(946076-26-2)
• EPA Substance Registry System: N-allyl-3-methoxybenzenesulfonamide(946076-26-2)

Safety Data

• Hazardous Substances Data: 946076-26-2(Hazardous Substances Data)

Upstream product

• 10130-74-2 m-Methoxybenzenesulfonyl chloride 
• 107-11-9 1-amino-2-propene 

Downstream Products

• 946076-67-1 ethyl 4-ethoxythiocarbonylsulfanyl-5-(3-methoxybenzenesulfonylamino)pentanoate 
• 946076-89-7 C₂₀H₂₉NS₃O₇ 

Relevant articles and documents

Synthesis of substituted 3-arylpiperidines and 3-arylpyrrolidines by radical 1,4 and 1,2-aryl migrations

A route to 3-arylpiperidines and 3-arylpyrrolidines involving radical 1,4- and 1,2-aryl migrations has been explored. For the piperidines, the first route requires a xanthate addition to an N-allylarylsulfonamide, followed by acetylation and treatment with lauroyl peroxide to give the corresponding 1,4-aryl transfer product. This compound can be converted into the desired piperidine derivative following acidic hydrolysis. For the second approach to piperidines, addition of an α-keto xanthate to olefins of type 14 causes 1,2-aryl migration leading to an α,β-unsaturated ester, which can be converted into a piperidine by the action of ammonia or a primary amine and sodium cyanoborohydride. Substituted 3-arylpyrrolidines can be obtained by simply starting with an α-amido substituted xanthate.