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946089-61-8

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946089-61-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 946089-61-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,6,0,8 and 9 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 946089-61:
(8*9)+(7*4)+(6*6)+(5*0)+(4*8)+(3*9)+(2*6)+(1*1)=208
208 % 10 = 8
So 946089-61-8 is a valid CAS Registry Number.

946089-61-8Relevant articles and documents

Design, synthesis and biological evaluation of peptide derivatives of l-dopa as anti-parkinsonian agents

Zhou, Tao,Hider, Robert C.,Jenner, Peter,Campbell, Bruce,Hobbs, Christopher J.,Rose, Sarah,Jairaj, Mark,Tayarani-Binazir, Kayhan A.,Syme, Alexander

, p. 5279 - 5282 (2013/09/23)

A series of dipeptide derivatives of l-dopa were synthesized and investigated for their pharmacological activity using the unilaterally 6-hydroxydopamine (6-OHDA)-lesioned rat as an experimental model of Parkinson's disease. Among them, (S)-isopropyl 2-(2-amino-2-methylpropanamido)-3-(3,4- dihydroxyphenyl)propanoate (4g) was found to be the most active compound, with 106% AUC activity and 149% peak activity of l-dopa after oral administration.

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