73470-46-9

Usage

Uses

Used in Peptide Synthesis:
Tert-Butyl (1-amino-2-methyl-1-oxopropan-2-yl)carbamate is used as a protecting group for the amino group of specific amino acids during peptide synthesis. This allows chemists to selectively manipulate peptide chains, facilitating the synthesis of complex peptide structures.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, tert-Butyl (1-amino-2-methyl-1-oxopropan-2-yl)carbamate is employed in the synthesis of various pharmaceuticals. Its unique structure and reactivity contribute to the development of new drugs with specific therapeutic properties.
Used in Organic Chemical Reactions:
Tert-Butyl (1-amino-2-methyl-1-oxopropan-2-yl)carbamate also serves as a reagent in organic chemical reactions, where its carbamate and tert-butyl groups can participate in a variety of chemical transformations, aiding in the synthesis of diverse organic compounds.

Upstream product

• 30992-29-1 Boc-Aib-OH 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1195769-60-8 1,1-dimethylethyl {1-[5-(2-chloro-4-pyrimidinyl)-4-(3-{[(2,6-difluorophenyl)sulfonyl]amino}-2-fluorophenyl)-1,3-thiazol-2-yl]-1-methylethyl}carbamate 
• 1195769-61-9 1,1-dimethylethyl [1-(5-(2-chloro-4-pyrimidinyl)-4-{2-fluoro-3-[(3-furanylsulfonyl)amino]phenyl}-1,3-thiazol-2-yl)-1-methylethyl]carbamate 
• 1195769-59-5 1,1-dimethylethyl {1-[4-(3-amino-2-fluorophenyl)-5-(2-chloro-4-pyrimidinyl)-1,3-thiazol-2-yl]-1-methylethyl}carbamate 
• 320581-09-7 (2-amino-1,1-dimethyl-ethyl)-carbamic acid tert-butyl ester 
• 16252-90-7 2-amino-2-methylpropanamide 
• 946089-92-5 C₂₃H₃₆N₂O₇ 
• 946089-85-6 C₂₄H₃₆N₂O₇ 
• 946089-83-4 C₂₁H₃₂N₂O₇ 
• 946089-61-8 C₂₅H₃₂N₂O₇ 
• 946089-58-3 C₁₉H₂₈N₂O₇ 
• 17704-74-4 2-Amino-2-methyl-propionamide hydrochloride 
• 77-71-4 5,5-dimethyl-imidazolidine-2,4-dione 

Relevant academic research and scientific papers

ALKYLBORONIC ACIDS AS ARGINASE INHIBITORS

Provided are alkylboronic acids as arginase inhibitors represented by formula (I), or a pharmaceutically acceptable salt, stereoisomer, tautomer, or prodrug thereof and a pharmaceutical composition comprising said compounds.

DIPEPTIDE ANALOGS AS TGF-BETA INHIBITORS

The present disclosure is concerned with dipeptide analogs that are capable of inhibiting TGF-β and methods of treating cancers such as, for example, multiple myeloma and a hematologic malignancy, methods for immunotherapy, and methods of treating fibroti

HETEROCYCLIC COMPOUNDS AS ARGINASE INHIBITORS

The present invention relates to heterocyclic compounds as arginase inhibitors, in particular to a compound represented by Formula (I), or a pharmaceutically acceptable salt, stereoisomer or tautomer, or prodrug thereof and a pharmaceutical composition comprising said compound.

NOVEL PYRIDINE DERIVATIVES

The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.

PYRIDIN- 2 -AMIDES USEFUL AS CB2 AGONISTS

The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.

Isoselenocyanates derived from Boc/Z-amino acids: Synthesis, isolation, characterization, and application to the efficient synthesis of unsymmetrical selenoureas and selenoureidopeptidomimetics

Isoselenocyanates derived from Boc/Z-amino acids are prepared by the reaction of the corresponding isonitriles with selenium powder in presence of triethylamine at reflux. The utility of these new classes of isoselenocyanates in the preparation of selenoureidodipeptidomimetics possessing both amino as well as carboxy termini has been accomplished. The 1H NMR analysis confirmed that the protocol involving the conversion of isonitriles to isoselenocyanates and their use as coupling agents in assembling selenoureido derivatives is free from racemization.

DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-α]IMIDAZOLE-3- CARBOXYLIC ACID AMIDES

Derivatives of 6,7-dihydro-5H-imidazo[1,2-α]imidazole-3-carboxylic acid amide exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.

Design and synthesis of dipeptidyl nitriles as potent, selective, and reversible inhibitors of cathepsin C

A series of dipeptide nitriles with a thienyl alanine in P2 were identified as potent and selective cathepsin C inhibitors. Incorporation of a substituted cyclopropyl moiety in P1 effectively protects these derivatives against hydrolase activity in whole blood.

PYRIDINE DERIVATIVES AS SODIUM CHANNEL BLOCKERS

Compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein; each of R1 to R4 is independently selected from hydrogen and C1-4 alkyl, and each of rings A and B independently is optionally further substi

QUINAZOLINE DERIVATIVES

A quinazoline derivative of the formula (I) wherein: R1, R2, R3, R3a, R4, R5, R5a R6, R7, a, m and p are as defined in the description. Also claimed are pharmaceutical compositions containing the quinazoline derivative, the use of the quinazoline derivatives as medicaments and processes for the preparation of the quinazoline derivative. The quinazoline derivatives of formula (I), are useful in the treatment of hyperproliferative disorders such as a cancer.