94614-83-2

Usage

Uses

Used in Pharmaceutical Industry:
1-(2-bromoethyl)-1H-imidazole(SALTDATA: 0.8HBr 0.2H2O 0.05NaBr) is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a key component in the development of new drugs, particularly those targeting specific biological pathways or receptors.
Used in Chemical Research:
1-(2-bromoethyl)-1H-imidazole(SALTDATA: 0.8HBr 0.2H2O 0.05NaBr) is used as a research tool in the field of organic chemistry. Its properties and reactivity can be studied to gain insights into the behavior of imidazole-based compounds and their potential applications in various chemical processes.
Used in Material Science:
1-(2-bromoethyl)-1H-imidazole(SALTDATA: 0.8HBr 0.2H2O 0.05NaBr) is used as a building block in the development of new materials with specific properties. Its unique structure and reactivity can contribute to the creation of advanced materials for various applications, such as sensors, catalysts, or advanced materials for energy storage and conversion.

Upstream product

• 288-32-4 1H-imidazole 
• 107-04-0 1-Bromo-2-chloroethane 
• 1615-14-1 1-(2-Hydroxyethyl)imidazole 
• 106-93-4 ethylene dibromide 

Relevant academic research and scientific papers

Preparation method of imidazole ethyl vanillic acid ether sodium salt

The invention relates to the field of medicinal chemistry, and particularly relates to a preparation method of an imidazole ethyl vanillic acid ether sodium salt. The method is characterized in that imidazole is adopted as an initial raw material, strong

Anticonvulsant and antitubercular activities of 6-Phenyl/Biphenyl-4-yl-2- [2-(pyridin-2-ylamino)-ethyl]-and 6-(Biphenyl-4yl)-2-(2N-subtituted amin-1-yl)-ethyl derivatives of 4,5-dihydropyridazin-3(2H)-one

Some 6-Phenyl/Biphenyl-4-yl-2-[2-(pyridin-2-ylamino)-ethyl]/-2-(2N- subtituted amin-1-yl)-ethyl-4,5- dihydropyridazin-3(2H)-one (4a-h) were synthesized by reacting 6-phenyl/biphenyl-4,5-dihydropyridazin-3(2H)-one with bromoethyl derivatives of cyclic secondary amines and 2-aminopyridine. All the compounds, 4a-h, were evaluated as anticonvulsant by using maximum electro shock (MES) and isoniazid (INH) induced convulsion methods at 50mg/kg dose level, and as antitubercular by Microplate Almar Blue Assay (MABA) method. In anticonvulsant activity, phenytoin (25mg/kg) and sodium vaproate (50mg/kg) were used as reference drugs. All compounds (4a-h) showed significant anticonvulsant activities against both MES and INH methods, and compound g showed highest activity against MES method. In antitubercular activity, compounds 4c-4h showed 25 μg/ml MIC value, and compounds 4a-4b exhibited 50 μg/ml MIC value when compared with reference drugs [isoniazid (3.125 μg/ml), pyrizinamide (3.125μg/ml)] and (streptomycin 6.25μg/ml) MIC values, and found less potent than the reference drugs.

METHOD FOR PREPARATION OF REGENERATIVE IMIDAZOLIUM REAGENTS

The present invention relates to novel imidazolium compounds and improved method for the preparation of imidazolium salts. More specifically the invention describes preparation of 1,3-substituted imidazolium reagents whereby the reactive species can be regenerated upon consumption and readily re-usable for versatile chemical transformations. The syntheses of novel imidazolium salts are for applications as oxidizing agent in environmentally electrochemical reactions, internal electrolyte for durable reference electrode and lipophilic salts for anion chemical sensors.