94633-38-2Relevant academic research and scientific papers
Utilisation of 13C N.M.R. Spectroscopy for the Identification of E- and Z-α,β-Unsaturated Esters, Ketones and Nitriles.
Gregory, Barrie,Hinz, Werner,Jones, R. Alan,Arques, Jose Sepulveda
, p. 2801 - 2821 (2007/10/02)
Measurement of 3JCO,H coupling constants provides an unambiguous procedure for the configurational analysis of substituted 2- and 3-arylpropenoic esters and of E- and Z-2-arylbut-2-en-1,4-dioates, even when only one of the isomers is available for analysis.An analogous procedure can also be used for the configurational analysis of 3-arylpropenonitriles and of 4-arylbut-3-en-2-ones.
Pyrrole Studies. Part 28. The Effect of Steric Hindrance upon the Reaction of 2-Vinylpyrroles with Dimethyl Acetylenedicarboxylate
Jones, R. Alan,Saliente, Teresa Aznar,Arques, Jose Sepulveda
, p. 2541 - 2543 (2007/10/02)
Steric interaction between the N-substituent and the vinyl substituent of 1-substituted 1-(1-substituted pyrrol-2-yl)ethenes destabilises the cisoid conformation (1b), thereby inhibiting (?4+?2) cycloaddition reactions leading to dihydroindoles.Bulky N-substituents also sterically inhibit the Michael addition of dimethyl acetylenedicarboxylate at the 5-position of the pyrrole ring.
