946428-12-2Relevant academic research and scientific papers
A convenient procedure for the preparation of sulfonamidoureas using triphosgene
Safaei-Ghomi, Javad,Bamoniri, Abdolhamid,Abbaszadeh-Nooshabady, Aboalfazl
, p. 721 - 724 (2007)
An efficient method for the preparation of sulfonamidourea using triphosgene in organic solvents is reported. Sulfonylhydrazides and acetylsulfanilylhydrazide were transformed into the corresponding intermediates using triphosgene in 1,4-dioxane/water or tetrahydrofuran as solvents. These intermediates were converted in situ into symmetrical and unsymmetrical sulfonamidoureas in high yields and shorter periods of time related to previous methods.
