946524-36-3 Usage
Uses
Used in Pharmaceutical Industry:
Oleoylethanolamide-d4 is used as a research compound for studying the role of PPAR-α and its agonists in various physiological processes. It helps in understanding the mechanisms of action and potential therapeutic applications of N-oleoylethanolamide and related compounds.
Used in Drug Development:
Oleoylethanolamide-d4 is used as a tool in drug development to identify and optimize novel PPAR-α agonists with potential therapeutic benefits. It aids in the discovery of new drugs targeting metabolic disorders, inflammation, and other related conditions.
Used in Neuroscience Research:
Oleoylethanolamide-d4 is used as a research tool in neuroscience to investigate the role of central dopamine activity and its regulation by intestinal signals. This helps in understanding the interplay between caloric and hedonic homeostatic controllers and their implications in various neurological and psychiatric disorders.
Used in Obesity and Metabolic Research:
Oleoylethanolamide-d4 is used as a research compound in obesity and metabolic research to study the effects of PPAR-α agonists on energy homeostasis, lipid metabolism, and insulin sensitivity. This contributes to the development of potential therapeutic agents for the treatment of obesity, diabetes, and related metabolic disorders.
Used in Endocannabinoid System Research:
As a selective GPR55 agonist, oleoyl ethanolamide-d4 is used in research to explore the role of the endocannabinoid system in various physiological and pathological processes. This helps in understanding the potential therapeutic applications of modulating the endocannabinoid system in conditions such as pain, inflammation, and neurodegenerative disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 946524-36-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,6,5,2 and 4 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 946524-36:
(8*9)+(7*4)+(6*6)+(5*5)+(4*2)+(3*4)+(2*3)+(1*6)=193
193 % 10 = 3
So 946524-36-3 is a valid CAS Registry Number.
946524-36-3Relevant academic research and scientific papers
Quantitative method for the profiling of the endocannabinoid metabolome by LC-atmospheric pressure chemical ionization-MS
Williams, John,Wood, JodiAnne,Pandarinathan, Lakshmipathi,Karanian, David A.,Bahr, Ben A.,Vouros, Paul,Makriyannis, Alexandros
, p. 5582 - 5593 (2008/03/12)
The endocannabinoid system's biological significance continues to grow as novel endocannabinoid metabolites are discovered. Accordingly, a myopic view of the system that focuses solely on one or two endocannabinoids, such as anandamide or 2-arachidonoyl glycerol, is insufficient to describe the biological responses to perturbations of the system. Rather, the endocannabinoid metabolome as a whole must be analyzed. The work described here is based on liquid chromatography coupled with atmospheric pressure chemical ionization mass spectrometry. This method has been validated to quantify, in a single chromatographic run, the levels of 15 known or suspected metabolites of the endocannabinoid system in the rat brain and is applicable to other biological matrixes. We have obtained an endocannabinoid profile specifically for the frontal cortex of the rat brain and have determined anandamide level differences following the administration of the fatty acid amide hydrolase inhibitor AM374.
