946530-65-0Relevant academic research and scientific papers
ADENOSINE RECEPTOR ANTAGONISTS
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Page/Page column 31; Sheet 2, (2008/06/13)
The present application discloses locked nucleoside compounds of the Formula I which act as antagonists of adenosine receptors, in particular the adenosine A3 receptor, and the use of such adenosine A3 receptor compounds in medicine, e.g. for the treatmen
Design, synthesis, and biological evaluation of LNA nucleosides as adenosine A3 receptor ligands
Ravn, Jacob,Qvortrup, Katrine,Rosenbohm, Christoph,Koch, Troels
, p. 5440 - 5447 (2008/03/18)
We have prepared a series of adenosine analogs based on the bicyclo[2.2.1]heptane scaffold of locked nucleic acid (LNA) and tested them for both agonist and antagonist activity at the adenosine A3 receptor. The design of these derivatives was b
