946571-76-2

Basic information

• Product Name: (+)-D-1,5-bis-O-allyl-2,3,6-tris-O-benzyl-myo-inositol
• Synonyms: (+)-D-1,5-bis-O-allyl-2,3,6-tris-O-benzyl-myo-inositol
• CAS NO: 946571-76-2
• Molecular Weight: 530.661
• Mol File: 946571-76-2.mol

Chemical Properties

• CAS DataBase Reference: (+)-D-1,5-bis-O-allyl-2,3,6-tris-O-benzyl-myo-inositol(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-D-1,5-bis-O-allyl-2,3,6-tris-O-benzyl-myo-inositol(946571-76-2)
• EPA Substance Registry System: (+)-D-1,5-bis-O-allyl-2,3,6-tris-O-benzyl-myo-inositol(946571-76-2)

Safety Data

• Hazardous Substances Data: 946571-76-2(Hazardous Substances Data)

Upstream product

• 946419-42-7 (-)-D-1,5-bis-O-allyl-2,6-bis-O-benzyl-myo-inositol 
• 100-39-0 benzyl bromide 
• 114218-16-5 1D-(+)-1-O-allyl-2,3,6-tri-O-benzyl-myo-inositol 
• 106-95-6 allyl bromide 

Downstream Products

• 946419-49-4 (+)-D-1,5-bis-O-allyl-2,3,6-tris-O-benzyl-4-O-(4-methoxybenzyl)-myo-inositol 
• 946419-58-5 (-)-D-1,5-bis-O-allyl-4-O-[2-(allyloxy)ethyl]-2,3,6-tris-O-benzyl-myo-inositol 
• 946419-45-0 (-)-D-1,5-bis-O-allyl-2,3,6-tris-O-benzyl-4-O-methyl-myo-inositol 
• 946419-46-1 (+)-D-2,3,6-tris-O-benzyl-4-O-methyl-myo-inositol 
• 946419-60-9 (-)-D-4-O-(2-hydroxyethyl)-2,3,6-tris-O-benzyl-myo-inositol 
• 946419-55-2 (+)-D-2,3,6-tris-O-benzyl-4-O-(methylsulfonyl)-myo-inositol 1,5-bis(dibenzyl phosphate) 
• 946419-54-1 (+)-D-2,3,6-tris-O-benzyl-4-O-(di-n-butylphosphinyl)-myo-inositol 1,5-bis(dibenzyl phosphate) 
• 946419-53-0 (+)-D-2,3,6-tris-O-benzyl-4-O-(dimethylphosphinyl)-myo-inositol 1,5-bis(dibenzyl phosphate) 
• 946419-52-9 (+)-D-2,3,6-tris-O-benzyl-myo-inositol 1,5-bis(dibenzyl phosphate) 
• 946419-51-8 (+)-D-2,3,6-tris-O-benzyl-4-O-(methoxybenzyl)-myo-inositol 1,5-bis(dibenzyl phosphate) 
• 946419-50-7 (-)-D-2,3,6-tris-O-benzyl-4-O-(4-methoxybenzyl)-myo-inositol 
• 946419-47-2 (+)-D-2,3,6-tris-O-benzyl-4-O-methyl-myo-inositol 1,5-bis(dibenzyl phosphate) 

Relevant articles and documents

Synthesis and biological action of novel 4-position-modified derivatives of D-myo-inositol 1,4,5-trisphosphate

(Chemical Equation Presented) The design of a range of 4-position-modified D-myo-inositol 1,4,5-trisphosphate derivatives is described. The enantioselective synthesis of these compounds is reported, along with initial biological analysis, which indicates

The preparation of phosphorylated intermediates for the synthesis of racemic and chiral myo-inositol 1,4,5-trisphosphate and its phosphorothioate analogues

Reaction of racemic 1,2,4-tri-O-benzyl-myo-inositol 3- with bis(2,2,2-trichloroethyl) phosphorochloridate gave a mixture of the 3,5- and 3,6-bisphosphate derivatives which were difficult to separate and could not be phosphorylated further.The bisphosphates were synthesised by the phosphorylation of the 5- and 6-O-(cis-prop-1-enyl) derivatives of racemic 1,2,4-tri-O-benzyl-myo-inositol and subsequent acidic hydrolysis. 1D-2,3,6-Tri-O-benzyl-1,4-di-O-(cis-prop-1-enyl)-myo-inositol was converted into crystalline 1D-2,3,6-tri-O-benzyl-myo-inositol 1,4-bis(dibenzyl phosphate), and thence into the crystalline 1,4,5-tris(dibenzyl phosphate) which was also obtained, using dibenzyloxy(diisopropylamino)phosphine, from 1D-2,3,6-tri-O-benzyl-myo-inositol.The latter compound was converted, using bis(2-cyanoethoxy)(diisopropylamino)phosphine, into the crystalline 1,4,5-tris which was also obtained from the 4,5-bis.Both the tris and the tris(dibenzyl phosphate) are intermediates suitable for the synthesis of 1,4,5-IP3.