946833-21-2

Upstream product

• 133788-99-5 2-fluoro-1-methoxy-4-methoxymethoxy-benzene 
• 452-11-9 3-fluoro-4-methoxyphenol 
• 946833-20-1 acetic acid 3-fluoro-4-methoxyphenyl ester 
• 455-91-4 1-(3-fluoro-4-methoxyphenyl)ethanone 
• 677323-83-0 4-[(2-fluoro-3-methoxy-6-methoxymethoxy-phenyl)-hydroxy-methyl]-benzoicacidmethylester 

Relevant academic research and scientific papers

LABELED PKG-1-ALPHA-BINDING COMPOUNDS AND THEIR USE IN IMAGING AND QUANTIFYING PAIN

The present invention relates to the use of compounds that selectively bind to activated protein kinase G1 alpha for imaging the anatomic basis for chronic pain. Such imaging may also be used to objectively quantify chronic pain. Specifically, fluorine-18

Neuronal Pain Pathway Modulators

The present invention relates to compounds that may be used to inhibit activation of protein kinase G (“PKG”). It is based, at least in part, on the discovery of the tertiary structure of PKG and the identification of molecules that either bind to the act