946837-99-6

Basic information

• Product Name: 6-BroMo-4-Methyl-1,2,3,4-tetrahydroquinoline
• Synonyms: 6-BroMo-4-Methyl-1,2,3,4-tetrahydroquinoline
• CAS NO: 946837-99-6
• Molecular Formula: C10H12BrN
• Molecular Weight: 226.11298
• Mol File: 946837-99-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 273.9±39.0 °C(Predicted)
• Appearance: /
• Density: 1.342±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 4.30±0.40(Predicted)
• CAS DataBase Reference: 6-BroMo-4-Methyl-1,2,3,4-tetrahydroquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6-BroMo-4-Methyl-1,2,3,4-tetrahydroquinoline(946837-99-6)
• EPA Substance Registry System: 6-BroMo-4-Methyl-1,2,3,4-tetrahydroquinoline(946837-99-6)

Safety Data

• Hazardous Substances Data: 946837-99-6(Hazardous Substances Data)

Usage

General Description

6-Bromo-4-methyl-1,2,3,4-tetrahydroquinoline is a chemical compound with the molecular formula C10H11BrN. It is a derivative of tetrahydroquinoline and contains a bromine atom and a methyl group. 6-BroMo-4-Methyl-1,2,3,4-tetrahydroquinoline has potential applications in the pharmaceutical industry, specifically in the development of new drugs and pharmaceutical products. Its unique structure and properties make it an interesting molecule for further research and exploration. Studies have shown that this compound exhibits biological activity, particularly in interactions with certain enzymes and receptors, making it a valuable chemical for medicinal chemistry research. Additionally, it may have potential uses in the synthesis of other organic compounds and in the development of new materials with specific properties.

Upstream product

• 66416-72-6 4-bromo-2-iodoaniline 
• 19343-78-3 4-methyl-1,2,3,4-tetrahydroquinoline 
• 491-35-0 C₆H₄NCH₂CHCCH₂ 
• 201230-82-2 carbon monoxide 
• 194782-61-1 4-bromo-2-(prop-1-en-2-yl)aniline 

Relevant articles and documents

Visible Light Photocatalytic Synthesis of Tetrahydroquinolines Under Batch and Flow Conditions

In this work, we describe the use of visible light and a photocatalytic system for the cyclization of iodoaryl vinyl derivatives to tetrahydroquinoline structures. The reaction proceeds under very mild conditions, tolerates different functional groups and more importantly, the method allows the synthesis of N-free tetrahydroquinolines from N-unprotected starting materials. In addition, the reaction can also be performed using flow-chemistry. Finally, a mechanistic proposal based on some mechanistic studies has been described.

Rhodium(I)-catalyzed hydroaminomethylation of 2-isopropenylanilines as a novel route to 1,2,3,4-tetrahydroquinolines

A new atom economical approach for the preparation of 1,2,3,4- tetrahydroquinolines can be achieved by means of the intramolecular hydroaminomethylation of 2-isopropenylanilines, mediated by an ionic diamino rhodium catalyst that does not require phosphine - this reaction is highly chemo- and regioselective, and it occurs in good isolated yields. The Royal Society of Chemistry.