94692-07-6

Upstream product

• 100-63-0 phenylhydrazine 
• 94692-05-4 ethyl 1-phenyl-5-(pyrrol-1-yl)-1H-pyrazole-4-carboxylate 
• 16078-71-0 ethyl 5-amino-1-phenyl-1H-pyrazole-4-carboxylate 
• 94692-06-5 1-phenyl-5-(pyrrol-1-yl)-1H-pyrazole-4-carbohydrazide 

Downstream Products

• 94692-10-1 N-[1-phenyl-5-(pyrrol-1-yl)-1H-pyrazol-4-yl]formamide 
• 867289-19-8 N-[1-phenyl-5-(pyrrol-1-yl)-1H-pyrazol-4-yl]acetamide 
• 867288-98-0 4-[1-phenyl-5-(pyrrol-1-yl)-1H-pyrazol-4-yl]semicarbazide 
• 94692-13-4 N,N'-bis<1-phenyl-5-(pyrrol-1-yl)pyrazol-4-yl>urea 
• 867289-01-8 1-[1-phenyl-5-(pyrrol-1-yl)-1H-pyrazol-4-yl]-3-(o-tolyl)urea 
• 867289-09-6 benzyl N-[1-phenyl-5-(pyrrol-1-yl)-1H-pyrazol-4-yl]carbamate 
• 94691-80-2 (1-Phenyl-1H-pyrazolo[4,3-e]pyrrolo[1,2-a]pyrazin-5-yl)-hydrazine 
• 94692-15-6 5-Chloro-1-phenyl-1H-pyrazolo[4,3-e]pyrrolo[1,2-a]pyrazine 
• 94692-09-8 1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-ylamine 

Relevant academic research and scientific papers

Pyrazoles and pyrazolo[4,3-e]pyrrolo[1,2-a]pyrazines, I. Synthesis and antimicrobial activity

The synthesis of the title compounds was achieved using 1-phenyl-5-(pyrrol-1-yl)-1H-pyrazole-3-carboxylic acid azide as starting material. The latter compound was allowed to react with alcohols and amines to afford the corresponding carbamates and urea de

Synthesis of novel pyrazolopyrrolopyrazines, potential analogs of sildenafil

Synthesis of novel pyrazolopyrrolopyrazines is herein described with the aim to reach new specific PDE-5 inhibitors of potential clinical interest in male erectile dysfunction.

NEW CONDENSED TRI- AND TETRACYCLIC PYRAZOLE RING SYSTEMS

1-Phenylpyrrazolopyrrolopyrazine and its 5-aza analogue were synthesized from ethyl 5-amino-1-phenylpyrazole-4-carboxylate.Additional azolo ring annelations on the pyrazine part of the first heterocycle afforded new tetracyclic systems with two common nitrogen atoms.