947-83-1Relevant academic research and scientific papers
Synthesis and α1-antagonist activity of derivatives of 4-chloro-5-{4- [2-(2-methoxyphenoxy)-ethyl]-1-piperazinyl}-3(2H)-pyridazinone
Strappaghetti, Giovannella,Barbaro, Roberta,Marucci, Gabrielle
, p. 773 - 779 (2000)
The synthesis and evaluation of the biological activity of new 4-chloro- 5-{4-[2-(2-methoxyphenoxy)-ethyl]-1-piperazinyl}-3(2H)-pyridazinone derivatives are reported. The blocking activity of these compounds was determined on the pre- and postsynaptic α-adrenoceptors of isolated rat vas deferens. (C) 2000 Editions scientifiques et medicales Elsevier SAS.
