947243-87-0

Basic information

• Product Name: ethyl 3-methoxy-4-[(3,5,6-trimethylpyrazin-2-yl)methoxy]benzoate
• Synonyms: ethyl 3-methoxy-4-[(3,5,6-trimethylpyrazin-2-yl)methoxy]benzoate
• CAS NO: 947243-87-0
• Molecular Weight: 330.384
• Mol File: 947243-87-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 3-methoxy-4-[(3,5,6-trimethylpyrazin-2-yl)methoxy]benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-methoxy-4-[(3,5,6-trimethylpyrazin-2-yl)methoxy]benzoate(947243-87-0)
• EPA Substance Registry System: ethyl 3-methoxy-4-[(3,5,6-trimethylpyrazin-2-yl)methoxy]benzoate(947243-87-0)

Safety Data

• Hazardous Substances Data: 947243-87-0(Hazardous Substances Data)

Upstream product

• 121-34-6 3-methoxy-4-hydroxybenzoic acid 
• 617-05-0 ethyl vanillate 
• 123624-90-8 2-(chloromethyl)-3,5,6-trimethylpyrazine 
• 79074-45-6 2-(bromomethyl)-3,5,6-trimethylpyrazine 
• 76494-51-4 Tetramethylpyrazine hydrochloride 

Downstream Products

• 947296-86-8 C₁₇H₂₁N₅O₃ 
• 1018438-89-5 3-methoxy-4-((3,5,6-trimethylpyrazin-2-yl)methoxy)benzoic acid 

Relevant articles and documents

Design, synthesis and biological evaluation of novel ligustrazinylated derivatives as potent cardiovascular agents

A series of novel ligustrazinylated derivatives was designed, synthesized and evaluated for their protective effects against hydrogen peroxide (H 2O2)-induced oxidative damage on ECV-304 cells, and also assayed for their inhibition effects on platelet aggregation induced by adenosine diphosphate (ADP). Biological results showed that some compounds exhibited moderate to potent activities in one or both of the assays. Among these compounds, compound 3 displayed the highest protective effect on the damaged ECV-304 cells with EC50 = 0.0040 mM, and compound 1c was the most active platelet aggregation inhibitor (EC50 = 0.40 mM). Structure-activity relationships were briefly discussed. The Royal Society of Chemistry 2013.