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4-METHYL-3-[[(3,5,6-TRIMETHYL-2-PYRAZINYL)METHYL]AMINO]BENZOIC ACID ETHYL ESTER is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

947243-99-4

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947243-99-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 947243-99-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,7,2,4 and 3 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 947243-99:
(8*9)+(7*4)+(6*7)+(5*2)+(4*4)+(3*3)+(2*9)+(1*9)=204
204 % 10 = 4
So 947243-99-4 is a valid CAS Registry Number.

947243-99-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 4-methyl-3-[(3,5,6-trimethylpyrazin-2-yl)methylamino]benzoate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:947243-99-4 SDS

947243-99-4Relevant academic research and scientific papers

Synthesis of novel ligustrazine derivatives as Na+/H+ exchange inhibitors

Ren, Mei,Dong, Jin,Xu, Yungen,Wen, Nan,Gong, Guoqing

experimental part, p. 2727 - 2736 (2011/08/06)

A novel series of 3,5,6-trimethylpyrazine-2-methoxy (or methylamino) substituted benzoyl-guanidine derivatives were designed and synthesized as Na+/H+ exchange (NHE) inhibitors. In this study, compounds with electron-withdrawing substituents on the benzene ring seemed to improve NHE-1 inhibitory activities. Compounds 6d, 6k, and 6l were found to be potent inhibitors of NHE-1 (IC50=3.0±1.6, 3.0±1.4, and 1.6±0.4nmol/l, resp.). Furthermore, they showed a remarkable reduction of infarct size in the rat myocardial infarction model in vivo.

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