94727-08-9Relevant academic research and scientific papers
Substituted phenyl-2-(1H)-pyrimidinones useful for treating cardiac insufficiency in a warm-blooded organism
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, (2008/06/13)
New substituted phenyl-2-(1H)-pyrimidinones of the general formula I STR1 in which R1 denotes an alkyl group having 1 to 4 carbon atoms, and R2 and R3, which can be identical or different, each denote hydrogen, halogen, cyano, a trifluoromethyl group, a hydroxyl group or an alkoxy group having 1 to 4 carbon atoms, it being possible for each alkyl moiety to be straight-chain or branched, and their tautomeric forms and their acid addition salts and N-oxides have a positive inotropic effect and can thus be used as medicaments for the treatment of cardiac insufficiency.
