94741-70-5

Basic information

• Product Name: 4-Amino-2-bromopyrimidine-5-carbonitrile
• Synonyms: 2-BROMO-4-AMINO-5-CYANOPYRIMIDINE;4-AMINO-2-BROMOPYRIMIDINE-5-CARBONITRILE;4-AMINO-2-BROMO-5-CYANOPYRIMIDINE;4-AMINO-2-BROMOPYRIMIDINE-5-CARBONITRILE,9 5%;4-Amino-2-bromo-pyrimidine-5-carbonitrile 4-Amino-2-bromo-pyrimidine-5-carbonitrile 4-Amino-2-bromo-pyrimidine-5-carbonitrile;4-Amino-2-bromo-5-cyanopyrimidine, 4-Amino-2-bromo-5-cyano-1,3-diazine
• CAS NO: 94741-70-5
• Molecular Formula: C₅H₃BrN₄
• Molecular Weight: 199.01
• Product Categories: Heterocyclic Compounds;Amines;Pyrazines, Pyrimidines & Pyridazines;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyrimidines;PyrimidinesHeterocyclic Building Blocks;pyrimidine;Heterocycle-Pyrimidine series
• Mol File: 94741-70-5.mol
• Article Data: 1

Chemical Properties

• Melting Point: 254 °C (dec.)(lit.)
• Boiling Point: 457.658 °C at 760 mmHg
• Flash Point: 230.584 °C
• Appearance: /
• Density: 1.944 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.67
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 4-Amino-2-bromopyrimidine-5-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-2-bromopyrimidine-5-carbonitrile(94741-70-5)
• EPA Substance Registry System: 4-Amino-2-bromopyrimidine-5-carbonitrile(94741-70-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 94741-70-5(Hazardous Substances Data)

Usage

General Description

4-Amino-2-bromopyrimidine-5-carbonitrile is a chemical compound with the molecular formula C6H4BrN5. It is an important intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of pyrimidine-based drugs. 4-Amino-2-bromopyrimidine-5-carbonitrile is a pyrimidine derivative, which is a heterocyclic aromatic organic compound containing two nitrogen atoms at positions 1 and 3 and a carbonitrile group at position 5. Its chemical properties make it highly versatile for use in medicinal and agricultural applications, and it is commonly utilized as a building block for the preparation of various bioactive compounds and functional materials. Additionally, it is known for its potential as an inhibitor of certain enzymes and receptors, making it a valuable tool for drug discovery and research in the pharmaceutical industry.

InChI:InChI=1/C5H3BrN4/c6-5-9-2-3(1-7)4(8)10-5/h2H,(H2,8,9,10)

Upstream product

• 113411-64-6 3-Cyanamino-2-cyanopropenenitrile sodium salt 

Relevant articles and documents

A Convenient Synthesis of 2-Substituted 4-Amino-5-pyrimidinecarbonitriles

Synthesis of the novel 2-halogenated 4-amino-5-pyrimidinecarbonitriles 3a,b starting from ethoxymethylenemalononitrile 1 and cyanamide is described.Nucleophilic substitution of the reactive halogen atom leads to the derivatives 5a-g,6 and 7a-h.