947536-07-4

Upstream product

• 3744-87-4 N-t-butyloxycarbonyl-DL-alanine 
• 5345-47-1 2-aminopyridin-3-carboxylic acid 
• 156-43-4 4-Ethoxyaniline 

Downstream Products

• 947536-13-2 rac-2-(1-amino-ethyl)-3-(4-ethoxy-phenyl)-3H-pyrido[2,3-d]pyrimidin-4-one 
• 855527-92-3 (+/-)-NBI-74330 
• 1397708-91-6 tert-butyl 4-[(N-{1-[3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyrido-[2,3-d]pyrimidin-2-yl]ethyl}-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamido)methyl]piperidine-1-carboxylate 
• 1397708-92-7 N-{1-[3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl]ethyl}-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-(piperidin-4-ylmethyl)acetamide 
• 1397708-93-8 N-{1-[3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl]ethyl}-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-[(1-methylpiperidin-4-yl)methyl]acetamide 
• 1397708-94-9 [3H]-RAMX₃ 
• 1397708-90-5 tert-butyl 4-[({1-[3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyrido-[2,3-d]pyrimidin-2-yl]ethyl}amino)methyl]piperidine-1-carboxylate 

Relevant academic research and scientific papers

Synthesis and Application of the First Radioligand Targeting the Allosteric Binding Pocket of Chemokine Receptor CXCR3

Strategies for the identification of allosteric modulators of chemokine receptors largely rely on various cell-based functional assays. Radioligand binding assays are typically not available for allosteric binding sites. We synthesized, purified, and appl