947548-14-3Relevant articles and documents
Novel inhibitors of 17β-hydroxysteroid dehydrogenase type 1: Templates for design
Allan, Gillian M.,Vicker, Nigel,Lawrence, Harshani R.,Tutill, Helena J.,Day, Joanna M.,Huchet, Marion,Ferrandis, Eric,Reed, Michael J.,Purohit, Atul,Potter, Barry V.L.
, p. 4438 - 4456 (2008/09/21)
The 17β-hydroxysteroid dehydrogenases (17β-HSDs) catalyze the interconversion between the oxidized and reduced forms of androgens and estrogens at the 17 position. The 17β-HSD type 1 enzyme (17β-HSD1) catalyzes the reduction of estrone (E1) to estradiol a
