947691-59-0

Basic information

• Product Name: BENZENAMINE, 4-ETHYL-3-METHOXY-
• Synonyms: BENZENAMINE, 4-ETHYL-3-METHOXY-;4-Ethyl-3-methoxyaniline
• CAS NO: 947691-59-0
• Molecular Formula: C₉H₁₃NO
• Molecular Weight: 151.208
• Mol File: 947691-59-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: BENZENAMINE, 4-ETHYL-3-METHOXY-(CAS DataBase Reference)
• NIST Chemistry Reference: BENZENAMINE, 4-ETHYL-3-METHOXY-(947691-59-0)
• EPA Substance Registry System: BENZENAMINE, 4-ETHYL-3-METHOXY-(947691-59-0)

Safety Data

• Hazardous Substances Data: 947691-59-0(Hazardous Substances Data)

Usage

General Description

Benzenamine, 4-ethyl-3-methoxy- is a chemical compound with the molecular formula C9H13NO. It is also known as 4-Ethyl-3-methoxyaniline and is a derivative of aniline. Benzenamine, 4-ethyl-3-methoxy- is commonly used as an intermediate in the synthesis of various pharmaceuticals, dyes, and pigments. It is a colorless to pale yellow liquid with a characteristic odor, and it is considered to be a hazardous substance that can cause irritation to the skin, eyes, and respiratory system. Additionally, it may be harmful if swallowed or inhaled and should be handled with proper safety precautions.

Upstream product

• 90610-19-8 2-ethyl-5-nitro-anisole 
• 74-84-0 ethane 
• 536-90-3 m-Anisidine 
• 34557-54-5 methane 

Downstream Products

• 947691-60-3 N-(4-ethyl-3-methoxyphenyl)acetamide 

Relevant articles and documents

PHOSPHODIESTERASE 10 INHIBITORS

The present invention if directed to certain cinnoline compounds that are PDE10 inhibitors, pharmaceutical compositions containing such compounds and processes for preparing such compounds. The invention is also directed to methods of treating diseases mediated by PDE10 enzyme, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.

Intramolecular Selectivity of the Alkylation of Substituted Anilines by Gaseous Cations

The intramolecular selectivity of the electrophilic reactions of Et(1+), i-Pr(1+), and Me2F(1+) cations with substituted anilines, including m-toluidine, m-anisidine, and m- and p-fluoroaniline, has been investigated in the dilute gas state at pressures ranging from 100 to 720 torr by a radiolytic technique, complemented by chemical ionization mass spectrometry.The results indicate an appreciable kinetic bias for the nitrogen atom, leading to predominant N-methylation by Me2F(1+).The reactivity of the carbenium ions is complicated by the simultaneous occurrence of proton transfer, in particular to the NH2 group, which increases the relative extent of ring alkylation.The positional selectivity is characterized, aside from the usual orienting effects of the substituents, by the enchanced reactivity of the ring positions ortho to an n-type substituent, irrespective of its activating or deactivating properties.The effect is traced to the preliminary formation of an electrostatic adduct between the aniline and the gaseous electrophile.