94795-73-0

Upstream product

• 94795-72-9 1,2-O-isopropylidene-5-O-benzoyl-3-O-trifluoromethanesulfonyl-α-D-xylofuranose 
• 98-88-4 benzoyl chloride 
• 6022-96-4 5-O-benzoyl-α-D-xylofuranose 
• 20031-21-4 1,2-O-isopropylidene-α-D-xylose 
• 14260-64-1 (3aR)-2,2-dimethyl-(3ar,6ac)-3a,6a-dihydro-furo[2,3-d][1,3]dioxole-5-carbaldehyde 
• 15919-16-1 5-β-formyl-4-β-O-tosyl-2α,3α-O-isopropylidenetetrahydrofuran 
• 111730-08-6 3-deoxy-1,2-O-isopropylidene-α-D-glyceropent-3-enofuranose 

Downstream Products

• 937181-56-1 5-O-benzoyl-3-deoxy-1,2-O-isopropylidene-3,4-C-(difluoromethylene)-β-L-arabinofuranose 
• 937181-58-3 9-(2-O-acetyl-5-O-benzoyl-3-deoxy-3,4-C-(difluoromethylene)-α-L-arabinofuranosyl)adenine 
• 937181-57-2 1,2-di-O-acetyl-5-O-benzoyl-3-deoxy-3,4-C-(difluoromethylene)-L-arabinofuranose 
• 111730-18-8 3-deoxy-1,2-O-isopropylidene-1-O-methyl-3-iodo-5-O-benzoyl-D-threo(erythro)-pent-4-ulose 
• 111730-21-3 3-deoxy-1,2-O-isopropylidene-3-iodo-4-methoxy-5-O-benzoyl-α-D-xylopentofuranose 
• 111730-19-9 3-deoxy-1-O-methyl-1,2-O-isopropylidene-3-bromo-5-O-benzoyl-D-threo(erythro)-pent-4-ulose 
• 112265-61-9 3-deoxy-1,2-O-isopropylidene-3-bromo-4-methoxy-5-O-benzoyl-α-D-xylopentofuranose 
• 111730-23-5 3-deoxy-1-fluoro-1,2-O-isopropylidene-3-bromo-5-O-benzoyl-D-threo(erythro)-pent-4-ulose 
• 111730-25-7 3-deoxy-1,2-O-isopropylidene-3-bromo-4-fluoro-5-O-benzoyl-α-D-xylopentofuranose 

Relevant academic research and scientific papers

Synthesis of 3′-deoxynucleosides with 2-oxabicyclo[3.1.0]hexane sugar moieties: Addition of difluorocarbene to a 3′,4′-unsaturated uridine derivative and 1,2-dihydrofurans derived from D- and L-xylose

(Chemical Equation Presented) Syntheses of 3′-deoxy analogues of adenosine, cytidine, and uridine with a 2,2-difluorocyclopropane ring fused at C3′-C4′ are described. Treatment of a 2′,5′-protected- 3′,4′-unsaturated derivative of uridine with difluorocar

Methyl 5-O-benzoyl-2,3-oxazole-D-ribofuranoside: A useful intermediate for the synthesis of conformationally restrained nucleosides

The synthesis of methyl 5-O-benzoyl-2,3-oxazole-D-ribofuranoside, a tetrahydrofuro [3,4-d]oxazole is described. The key step involves the reaction of methyl 3-amino-3-deoxy-5-O-benzoyl-D-ribofuranoside with N,N-dimethylformamide dimethyl acetal with cyclisation to the 2,3-oxazole via a prototropic rearrangement-elimination reaction.

REACTION OF Δ3-UNSATURATED PENTOFURANOSES WITH ELECTROPHILIC REAGENTS

The reaction of the 5-O-derivatives of 3-deoxy-1,2-O-isopropylidene-α-D-glyceropent-3-enofuranose with iodine or bromine in methanol in the presence of silver carbonate or in inert solvents in the presence of thallium fluoride leads mainly to a mixture of the cyclic product from addition at the Δ3-double bond and an acyclic 3-halogeno-4-keto derivative.In some cases only one reaction product is formed.With mercuric acetate in methanol the opening of the furanose ring in the initial compound is not observed.

STRUCTURE AND TOTAL SYNTHESIS OF CHRYSCANDIN, A NEW ANTIFUNGAL ANTIBIOTIC

The structure elucidation and total synthesis of chryscandin (1), a new antifungal antibiotic produced by Chrysosporium pannorum No.4629, is reported.