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Benzene, 1,2,4-tris(1-methylethenyl)-, also known as 1,3,5-trimethyl-1,3,5-cyclohexatriene or 1,2,4-trimethylbenzene, is an organic compound with the chemical formula C9H12. It is a derivative of benzene, where three hydrogen atoms are replaced by methyl groups (CH3) at the 1, 2, and 4 positions. Benzene, 1,2,4-tris(1-methylethenyl)- is a colorless liquid with a strong aromatic odor and is insoluble in water. It is used as a chemical intermediate in the synthesis of various organic compounds, such as dyes, pharmaceuticals, and polymers. Due to its potential health risks, exposure to 1,2,4-trimethylbenzene should be minimized, and appropriate safety measures should be taken when handling this substance.

948-33-4

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948-33-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 948-33-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,4 and 8 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 948-33:
(5*9)+(4*4)+(3*8)+(2*3)+(1*3)=94
94 % 10 = 4
So 948-33-4 is a valid CAS Registry Number.

948-33-4Downstream Products

948-33-4Relevant academic research and scientific papers

Can the Ti(OiPr)4/nBuLi combination of reagents function as a catalyst for [2+2+2] alkyne cyclotrimerisation reactions?

Siemiaszko, Gabriela,Six, Yvan

supporting information, p. 20219 - 20226 (2018/12/13)

Catalysis of the cyclotrimerisation of alkynes with the Ti(OiPr)4/nBuLi system was studied, leading to the development of a particularly convenient and reliable protocol. This method allows the [2+2+2] cycloaddition reaction to proceed within a few minutes under microwave conditions, with generally good selectivity from a variety of aromatic and aliphatic alkynes.

Iron-Catalyzed Cyclotrimerization of Terminal Alkynes by Dual Catalyst Activation in the Absence of Reductants

Brenna, Davide,Villa, Matteo,Gieshoff, Tim N.,Fischer, Fabian,Hapke, Marko,Jacobi von Wangelin, Axel

supporting information, p. 8451 - 8454 (2017/07/11)

Catalyzing C?C bond-forming reactions with earth-abundant metals under mild conditions is at the heart of sustainable synthesis. The cyclotrimerization of alkynes is a valuable atom-efficient reaction in organic synthesis that is enabled by several metal catalysts, including iron. This study reports an effective iron-catalyzed cyclotrimerization for the regioselective synthesis of 1,2,4-substituted arenes (1 mol % catalyst, toluene, 20 °C, 5 min). A dual activation mechanism (substrate deprotonation, reductive elimination) renders the simple FeII precatalyst highly active in the absence of any reductant.

A simple cobalt catalyst system for the efficient and regioselective cyclotrimerisation of alkynes

Hilt, Gerhard,Vogler, Thomas,Hess, Wilfried,Galbiati, Fabrizio

, p. 1474 - 1475 (2007/10/03)

The intermolecular cyclotrimerisation of terminal and internal alkynes can be catalysed by simple cobalt complexes such as a CoBr2(diimine) under mild reaction conditions when treated with zinc and zinc iodide with high regioselectivity in excellent yields. The Royal Society of Chemistry 2005.

STRUCTURAL INVESTIGATION ON SOME TRISISOPROPENYL-BENZENES BY THEORETICAL AND GAS-PHASE UV PHOTOELECTRON SPECTROSCOPIC STUDY

Andoni, E.,Bossa, M.,Carusi, P.,Cauletti, C.,Furlani, A.

, p. 115 - 122 (2007/10/02)

The structure of 1,3,5-trisisopropenylbenzene (I) and 1,2,4-trisiopropenylbenzene (II) was investigated by gas-phase UV photoelectron spectroscopy (UPS) and theoretical (HAM 3) calculations.In the case of compound I we found that the geometrical parameters do not affect appreciably the ordering and spacing of the highest occupied molecular orbitals whereas in II agreement between experimental and calculated IEs was found only for some geometries, characterized also by the lowest total energies.This difference is reflected in the spacing of energy levels in the two molecules.

POLYMERS FROM MONOSUBSTITUTED ACETYLENES

Furlani, Anita,Russo, Maria Vittoria,Carusi, Paola,Licoccia, Silvia,Leoni, Emidio,Valenti, Guido

, p. 671 - 676 (2007/10/02)

The reactivity of bromopropyne, chloropropyne, propargyl alcohol and isopropenylacetylene in the presence of various bisphosphine nickel complexes has been examined.Polymers of bromopropyne, and propargyl alcohol are obtained in the presence of Ni(NCS)2(

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