94818-47-0

Upstream product

• 84519-53-9 (4R,5S)-2,2,5-trimethyl-1,3-dioxolane-4-carbaldehyde 
• 100-46-9 benzylamine 
• 73679-53-5 (E,4'S,5'S)-ethyl 3-(2',2',5'-trimethyl-1',3'-dioxolan-4'-yl)acrylate 
• 158569-45-0 (4S,5S,2E)-4,5-isopropylidenedioxyhex-2-ene-1-ol 

Downstream Products

• 120408-89-1 (S)-1-Benzyl-3,3-difluoro-4-((4S,5S)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-azetidin-2-one 
• 120315-99-3 (R)-1-Benzyl-3,3-difluoro-4-((4S,5S)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-azetidin-2-one 
• 120316-06-5 (S)-3-Benzylamino-2,2-difluoro-3-((4S,5S)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-propionic acid methyl ester 
• 120316-10-1 α-1,4-O-diacetyl-N-benzyldaunosamine 
• 120316-11-2 β-1,4-O-diacetyl-N-benzyldaunosamine 
• 120316-12-3 diacetyl α-L-2,3,6-trideoxy-3-N-benzylamino-2,2-difluorogulopyranoside 
• 120316-13-4 diacetyl β-L-2,3,6-trideoxy-3-N-benzylamino-2,2-difluorogulopyranoside 
• 120316-06-5 (R)-3-Benzylamino-2,2-difluoro-3-((4S,5S)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-propionic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of amino sugars through a highly diastereoselective dipolar cycloaddition. Enantioselective synthesis of the carbohydrate segment of Sch 38516

A concise and stereoselective route for the synthesis of the carbohydrate moiety of the antifungal agent Sch 38516 is described. The synthesis scheme includes a dipolar cycloaddition, which is rendered diastereoselective through the use of a readily available and easily removable chiral auxiliary.